Document Detail


Characterization of the FIDDLEHEAD gene of Arabidopsis reveals a link between adhesion response and cell differentiation in the epidermis.
MedLine Citation:
PMID:  10559443     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the isolation of the FIDDLEHEAD (FDH) gene of Arabidopsis by transposon tagging. Three mutant alleles of FDH carrying insertions of the Enhancer/Suppressor-mutator transposon and one stable allele with a transposon footprint were generated in the Arabidopsis ecotype Columbia genetic background. Closer examination of the adaxial epidermis of rosette leaves revealed that in addition to provoking the previously described fusion phenotype in leaves and floral organs, mutations in FDH have a deleterious effect on trichome differentiation. FDH transcripts were detected exclusively in the epidermis of young vegetative and floral organs. Plants overexpressing FDH under control of the cauliflower mosaic virus 35S promoter segregated fdh phenocopies, wild-type individuals, and plants showing severe retardation of growth and development. The dwarf plants displayed the most FDH expression, the fdh phenocopies generally the least. The protein product of FDH shows similarity to condensing enzymes involved in lipid biosynthesis, particularly those of the FATTY ACID ELONGATION family.
Authors:
A Yephremov; E Wisman; P Huijser; C Huijser; K Wellesen; H Saedler
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Plant cell     Volume:  11     ISSN:  1040-4651     ISO Abbreviation:  Plant Cell     Publication Date:  1999 Nov 
Date Detail:
Created Date:  2000-01-11     Completed Date:  2000-01-11     Revised Date:  2010-09-13    
Medline Journal Info:
Nlm Unique ID:  9208688     Medline TA:  Plant Cell     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2187-201     Citation Subset:  IM    
Affiliation:
Max-Planck-Institut für Züchtungsforschung, Carl von Linné Weg 10, 50829 Cologne, Germany. efremov@mpiz-koeln.mpg.de
Data Bank Information
Bank Name/Acc. No.:
GENBANK/AJ010713
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MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Arabidopsis / cytology,  genetics*,  physiology
Arabidopsis Proteins*
Base Sequence
Cell Adhesion
Cell Differentiation
Chromosome Mapping*
Cloning, Molecular
DNA Transposable Elements
Databases, Factual
Gene Expression Regulation, Developmental
Gene Expression Regulation, Plant*
Genes, Plant
Molecular Sequence Data
Mutagenesis, Insertional
Plant Leaves
Plant Proteins / chemistry,  genetics*,  metabolism
RNA, Messenger / genetics
Recombinant Proteins / chemistry,  metabolism
Sequence Alignment
Sequence Homology, Amino Acid
Transcription, Genetic
Chemical
Reg. No./Substance:
0/Arabidopsis Proteins; 0/At2g26250 protein, Arabidopsis; 0/DNA Transposable Elements; 0/Plant Proteins; 0/RNA, Messenger; 0/Recombinant Proteins
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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