Document Detail


Characteristics of visual hallucinations in Parkinson disease dementia and dementia with lewy bodies.
MedLine Citation:
PMID:  16473980     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Parkinson disease dementia (PDD) and dementia with Lewy bodies (DLB) have overlapping clinical and pathologic features. Recurrent visual hallucinations (RVH) are common in both disorders. The authors have compared details of hallucination characteristics and associated neuropsychiatric features in DLB and PDD.
METHODS: This is a descriptive, cross-sectional study using the Institute of Psychiatry Visual Hallucinations Interview (IP-VHI) to explore self-reported frequency, duration, and phenomenology of RVH in PDD and DLB. The caregivers' ratings of hallucinations and other neuropsychiatric features were elicited with the Neuropsychiatric Inventory (NPI).
RESULTS: Fifty-six patients (35 PDD; 21 DLB) with RVH were assessed. Hallucination characteristics were similar in both disorders. Simple hallucinations were rare. Most patients experienced complex hallucinations daily, normally lasting minutes. They commonly saw people or animals and the experiences were usually perceived as unpleasant. NPI anxiety scores were higher in PDD. Neuropsychiatric symptoms coexisting with hallucinations were apathy, sleep disturbance, and anxiety.
CONCLUSIONS: Patients with mild to moderate dementia can provide detailed information about their hallucinations. Characteristics of RVH were similar in PDD and DLB, and phenomenology suggests the involvement of dorsal and ventral visual pathways in their generation. The coexistence of RVH with anxiety, apathy, and sleep disturbance is likely to impair patients' quality of life and may have treatment implications.
Authors:
Urs P Mosimann; Elise N Rowan; Cassie E Partington; Daniel Collerton; Elizabeth Littlewood; John T O'Brien; David J Burn; Ian G McKeith
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry     Volume:  14     ISSN:  1064-7481     ISO Abbreviation:  Am J Geriatr Psychiatry     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-02-13     Completed Date:  2006-05-11     Revised Date:  2014-02-19    
Medline Journal Info:
Nlm Unique ID:  9309609     Medline TA:  Am J Geriatr Psychiatry     Country:  United States    
Other Details:
Languages:  eng     Pagination:  153-60     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Anxiety / epidemiology
Female
Hallucinations / diagnosis*,  epidemiology*
Humans
Lewy Body Disease / epidemiology*
Male
Parkinson Disease / epidemiology*
Questionnaires
Severity of Illness Index
Sleep Disorders / epidemiology
Grant Support
ID/Acronym/Agency:
G0400074//Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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