Document Detail

Characteristics of sodium sensitivity in Korean populations.
MedLine Citation:
PMID:  21860557     Owner:  NLM     Status:  MEDLINE    
Sodium sensitivity (SS) is a variable response of blood pressure (BP) to changes in sodium intake. The present study evaluated the existence and the characteristics of subjects with SS in Koreans. One hundred one subjects with (n = 31, 57.7 ± 9.8 yr) or without hypertension (n = 70, 40.8 ± 16.5 yr) were given a low-sodium dietary approache to stop hypertension (DASH) diet (LSD) for 7 days and a high-sodium DASH diet (HSD) for the following 7 days. The prevalence of SS in the present study population was 27.7% (17.6% in the non-hypertensive subjects and 51.6% in the hypertensive subjects). Analysis of the non-hypertensive subjects showed that systolic BP, diastolic BP, and mean arterial pressure at baseline and after HSD were higher in the subjects with SS than the subjects without SS, and there were no differences after LSD. In the hypertensive subjects, there was no difference in the BP at baseline and after HSD whether or not the subjects had SS. However, the systolic BP of hypertensive subjects with SS was lower than hypertensive subjects without SS after LSD. In the present study population, subjects with SS have distinctive BP features unlike to subjects without SS.
Sung Joon Shin; Chi Yeon Lim; Moo-Yong Rhee; Sang Woo Oh; Sang Hoon Na; Yongsoon Park; Cho-Il Kim; Seo-Young Kim; Jong-Wook Kim; Hye-Kyung Park
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-07-27
Journal Detail:
Title:  Journal of Korean medical science     Volume:  26     ISSN:  1598-6357     ISO Abbreviation:  J. Korean Med. Sci.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-23     Completed Date:  2011-12-12     Revised Date:  2013-06-27    
Medline Journal Info:
Nlm Unique ID:  8703518     Medline TA:  J Korean Med Sci     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  1061-7     Citation Subset:  IM    
Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University, Goyang, Korea.
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MeSH Terms
Blood Chemical Analysis
Blood Pressure / drug effects,  physiology
Diet, Sodium-Restricted / methods
Hypertension / diet therapy*,  etiology,  prevention & control
Middle Aged
Republic of Korea
Sodium, Dietary / adverse effects*
Young Adult
Reg. No./Substance:
0/Sodium, Dietary

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