| Characteristics and predictors of recurrence of anterior and intermediate uveitis in a Canadian referral centre. | |
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MedLine Citation:
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PMID: 20379299 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To describe the characteristics of uveitis in a Canadian referral centre and to identify predictors of uveitis recurrence. DESIGN: Retrospective cohort study. PARTICIPANTS: Two hundred eighty-five patients with anterior uveitis, intermediate uveitis, or panuveitis. METHODS: We conducted a retrospective study of all patients presenting with anterior uveitis, intermediate uveitis, or panuveitis to the sole uveitis subspecialist at the regional referral centre between September 2004 and March 2006. Patients with posterior uveitis were excluded. Characteristics such as onset, severity, anatomical subtype, systemic association or etiology, recurrence rate, response to treatment, and complications were identified. Regression analysis was used to determine predictors of uveitis recurrence. RESULTS: Three hundred sixty-four eyes from 285 patients were enrolled. Anatomical subtypes were 313 anterior, 36 intermediate, and 15 panuveitis. Systemic associations included ankylosing spondylitis (11.3%), inflammatory bowel disease (6%), sarcoidosis (4.1%), and herpes infections (3.8%). A human leukocyte antigen B27 (HLA-B27)-related association was found in 86 patients (23.6%). Patients with uveitis-associated complications or back symptomatology were more likely to have a recurrence (odds ratios 3.86 and 2.29, respectively). CONCLUSIONS: Common associations were ankylosing spondylitis, inflammatory bowel disease, sarcoidosis, and herpes infections. Patients with uveitis complications and back symptomatology were significantly more likely to have uveitis recurrences. |
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Authors:
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Stanley M Chan; Kenman D Gan; Ezekiel Weis |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Volume: 45 ISSN: 0008-4182 ISO Abbreviation: Can. J. Ophthalmol. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-09 Completed Date: 2010-05-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0045312 Medline TA: Can J Ophthalmol Country: Canada |
Other Details:
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Languages: eng Pagination: 144-8 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University of Alberta, 2306-10240 Kingsway Ave., Edmonton, AB T5H3V9. stanley.chan@ualberta.ca |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Canada Child Child, Preschool Female Herpes Simplex / complications Humans Inflammatory Bowel Diseases / complications Male Middle Aged Recurrence Referral and Consultation / statistics & numerical data Retrospective Studies Sarcoidosis / complications Spondylitis, Ankylosing / complications Uveitis, Anterior / diagnosis, etiology* Uveitis, Intermediate / diagnosis, etiology* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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