Document Detail

Characteristics of mechanical heart valve cavitation in a pneumatic ventricular assist device.
MedLine Citation:
PMID:  18422801     Owner:  NLM     Status:  MEDLINE    
In previous studies, we investigated the mechanism of mechanical heart valve (MHV) cavitation and cavitation intensity with a nonsynchronized experiment system. Our group is currently developing a pneumatic ventricular assist device (PVAD), and in this study we investigated MHV cavitation intensity in the PVAD using a synchronized analysis of the cavitation images and the acoustic signal of cavitation bubbles. A 23-mm Medtronic Hall valve with an opening angle of 70 degrees was mounted in the mitral position of the PVAD after removing the sewing ring. A function generator provided a square signal, which used the trigger signal of the electrocardiogram R wave (ECG-R) mode of the control-drive console for circulatory support. This square signal was delayed by a delay circuit and was then used as the trigger signal for a pressure sensor and a high-speed video camera. The data were stored using a digital oscilloscope at a 1-MHz sampling rate, and then the pressure signal was band-pass filtered between 35 and 200 kHz using a digital filter. The band-pass filtered root mean squared (RMS) pressure and cavitation cycle duration were used as an index of cavitation intensity. The cavitation bubbles were concentrated at the valve stop, and the cavitation cycle duration and RMS pressure increased as the heart rate and driving pressure increased. At the low valve-closing velocity, bubble cavitation was observed near the valve stop. However, at the fast valve-closing velocity, cloud cavitation was observed. A high-frequency signal wave was generated when the bubbles collapsed. The cavitation cycle duration and RMS pressure increased as the valve-closing velocity increased linearly.
Hwansung Lee; Yoshiyuki Taenaka
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-04-16
Journal Detail:
Title:  Artificial organs     Volume:  32     ISSN:  1525-1594     ISO Abbreviation:  Artif Organs     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-06-04     Completed Date:  2008-07-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802778     Medline TA:  Artif Organs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  453-60     Citation Subset:  IM    
Department of Artificial Organs, Research Institute, National Cardiovascular Center, Osaka, Japan.
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MeSH Terms
Blood Flow Velocity / physiology
Heart Rate / physiology
Heart Valves / physiology*
Heart-Assist Devices*
Prosthesis Design / instrumentation*
Ventricular Pressure / physiology

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