Document Detail

Characteristics of images of angiographically proven normal coronary arteries acquired by adenosine-stress thallium-201 myocardial perfusion SPECT/CT-IQ[Symbol: see text]SPECT with CT attenuation correction changed stepwise.
MedLine Citation:
PMID:  25472779     Owner:  NLM     Status:  Publisher    
OBJECTIVE: Although several studies have shown the diagnostic and prognostic value of CT-based attenuation correction (AC) of single photon emission computed tomography (SPECT) images for diagnosing coronary artery disease (CAD), this issue remains a matter of debate. To clarify the characteristics of CT-AC SPECT images that might potentially improve diagnostic performance, we analyzed images acquired using adenosine-stress thallium-201 myocardial perfusion SPECT/CT equipped with IQ[Symbol: see text]SPECT (SPECT/CT-IQ[Symbol: see text]SPECT) from patients with angiographically proven normal coronary arteries after changing the CT attenuation correction (CT-AC) in a stepwise manner.
METHODS: We enrolled 72 patients (Male 36, Female 36) with normal coronary arteries according to findings of invasive coronary angiography or CT-angiography within three months after a SPECT/CT study. Projection images were reconstructed at CT-AC values of (-), 40, 60, 80 and 100 % using a CT number conversion program according to our definition and analyzed using polar maps according to sex.
RESULTS: CT attenuation corrected segments were located from the mid- and apical-inferior spread through the mid- and apical-septal regions and finally to the basal-anterior and basal- and mid-lateral regions in males, and from the mid-inferior region through the mid-septal and mid-anterior, and mid-lateral regions in females as the CT-AC values increased. Segments with maximal mean counts shifted from the apical-anterior to mid-anterolateral region under both stress and rest conditions in males, whereas such segments shifted from the apical-septal to the mid-anteroseptal region under both stress and rest conditions in females.
CONCLUSIONS: We clarified which part of the myocardium and to which degree CT-AC affects it in adenosine-stress thallium-201 myocardial perfusion SPECT/CT-IQ[Symbol: see text]SPECT images by changing the CT-AC value stepwise. We also identified sex-specific shifts of segments with maximal mean counts that changed as CT-AC values increased.
Teruyuki Takahashi; Haruki Tanaka; Nami Kozono; Yoshiki Tanakamaru; Naomi Idei; Norihiko Ohashi; Hideki Ohtsubo; Takenori Okada; Yuji Yasunobu; Shunichi Kaseda
Related Documents :
2057009 - Dystonia and akinesia due to pallidoputaminal lesions after disulfiram intoxication.
3539029 - Sonographic finding of the bright thalamus.
2433499 - Cranial computerized tomography in dihydropteridine reductase deficiency.
2980449 - Imaging studies in neonatal herpes simplex encephalitis.
16908579 - Serial mr imaging, diffusion tensor imaging, and mr spectroscopic findings in a child w...
17984749 - Herpes simplex virus type 2 encephalitis in an elderly immunocompetent male.
11932089 - Diverticular abscess presenting as prostate abscess and missed by abdominal ct scan.
8423129 - Correlative imaging of pelvic soft tissue sarcomas in children.
12197559 - Identification of chlamydia trachomatis dna in human papillomavirus (hpv) positive wome...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-12-4
Journal Detail:
Title:  Annals of nuclear medicine     Volume:  -     ISSN:  1864-6433     ISO Abbreviation:  Ann Nucl Med     Publication Date:  2014 Dec 
Date Detail:
Created Date:  2014-12-4     Completed Date:  -     Revised Date:  2014-12-5    
Medline Journal Info:
Nlm Unique ID:  8913398     Medline TA:  Ann Nucl Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Preparation of reduced graphite oxide with high volumetric capacitance in supercapacitors.
Next Document:  Neurotrophic keratopathy due to dorsolateral medullary infarction (Wallenberg Syndrome): case report...