Document Detail

Characteristics of coronary artery inflow and its significance in coronary pathophysiology.
MedLine Citation:
PMID:  8186399     Owner:  NLM     Status:  MEDLINE    
To obtain insights into transmural myocardial perfusion during coronary artery stenosis, we evaluated the characteristics of septal arterial blood flow velocity using a 20 MHz multichannel pulsed Doppler velocimeter. Septal arterial blood flow velocity was characterized by the presence of a retrograde blood velocity component. Thus, a substantial amount of blood that entered the myocardium during diastole flows backward to the proximal coronary arteries. This is evidence of the coronary slosh phenomenon. With coronary artery stenosis, the systolic retrograde flow was enhanced, and was augmented further by coronary vasodilation. Since the component of blood moving backward in systole does not contribute to the perfusion of the myocardial bed, an augmented coronary slosh phenomenon plays an important role in disturbing myocardial inflow in addition to the stenotic impeding effects on diastolic flow.
M Goto; A Kimura; K Tsujioka; F Kajiya
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biorheology     Volume:  30     ISSN:  0006-355X     ISO Abbreviation:  Biorheology     Publication Date:    1993 Sep-Dec
Date Detail:
Created Date:  1994-06-22     Completed Date:  1994-06-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372526     Medline TA:  Biorheology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  323-31     Citation Subset:  IM    
Department of Medical Engineering and Systems Cardiology, Kawasaki Medical School, Kurashiki, Japan.
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MeSH Terms
Arterial Occlusive Diseases / physiopathology*
Blood Flow Velocity
Coronary Circulation / physiology
Coronary Disease / physiopathology*
Coronary Vessels / physiopathology*
Diastole / physiology
Systole / physiology

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