| Characteristics and consequences of airway colonization by filamentous fungi in 201 adult patients with cystic fibrosis in France. | |
| | |
MedLine Citation:
|
PMID: 21067327 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
A total of 657 sputum samples from 201 cystic fibrosis adult patients were collected during a 24-month period (2005-2006). We retrospectively analyzed the fungal colonization of the respiratory tract of these individuals by linking medical records and microbiological data. Filamentous fungi were isolated from specimens of 65.6% of the patients, with Aspergillus fumigatus being the predominant species recovered as it was found in specimens of 56.7% of the patients. We observed no difference for gender, pancreatic status and cirrhosis in patients with or without A. fumigatus colonization. We found a higher percentage of recovery of Pseudomonas aeruginosa, Stenotrophomonas maltophilia and nontuberculous mycobacteria in patients with A. fumigatus colonization. During the follow-up period of the study, 8.9% of the patients were diagnosed with allergic bronchopulmonary aspergillosis (ABPA). By a multivariate analysis we demonstrated that Scedosporium apiospermum was significantly associated with ABPA (Odds ratio = 13 [2-80]) as opposed to A. fumigatus (Odds ratio = 1.58 [0.49-5.05]). |
| | |
Authors:
|
André Paugam; Marie-Thérèse Baixench; Nadine Demazes-Dufeu; Pierre-Régis Burgel; Elise Sauter; Reem Kanaan; Daniel Dusser; Jean Dupouy-Camet; Dominique Hubert |
Related Documents
:
|
8366507 - Arthropathies of cystic fibrosis: case reports and review of the literature. 19490807 - Radiological sinonasal findings in adults with cystic fibrosis. 15684297 - Long-term clearance from small airways in patients with cystic fibrosis. 3864357 - The role of the small intestine in cystic fibrosis patients. 19758197 - Human leukocyte antigen-drb1 and -dqb1 genotyping in lupus patients with and without an... 2013627 - Plasma histamine in patients with chronic renal failure and nephrotic syndrome. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Medical mycology : official publication of the International Society for Human and Animal Mycology Volume: 48 Suppl 1 ISSN: 1460-2709 ISO Abbreviation: Med. Mycol. Publication Date: 2010 Nov |
Date Detail:
|
Created Date: 2010-11-11 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9815835 Medline TA: Med Mycol Country: England |
Other Details:
|
Languages: eng Pagination: S32-6 Citation Subset: IM |
Affiliation:
|
Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, France. andre.paugam@cch.aphp.fr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Local innate host response and filamentous fungi in patients with cystic fibrosis.
Next Document: Clinical associations and prevalence of Scedosporium spp. in Australian cystic fibrosis patients: id...