Document Detail

Characteristics and Management of Patients With Acute Coronary Syndrome and Normal or Non-Significant Coronary Artery Disease: Results From Acute Coronary Syndrome Israeli Survey (ACSIS) 2004-2010.
MedLine Citation:
PMID:  25091099     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: An important subset of patients presenting with acute coronary syndrome (ACS) are found to have either normal coronaries (NCs) or non-obstructive coronary artery disease (NOCAD; lumen diameter narrowing <50%).
OBJECTIVES: To explore the characteristics and management strategies in this population in a real-world setting.
METHODS: The Acute Coronary Syndrome Israeli Survey (ACSIS) database was utilized to compare the characteristics and therapeutic approach for patients who underwent angiography for ACS and had either NC (n = 84; 2%), NOCAD (n = 79; 2%), or obstructive coronary artery disease (OCAD; n = 3523; 96%).
RESULTS: Baseline characteristics were comparable, save for a younger age and a higher proportion of females in the NC group (P<.001 for both). Prior to admission, chronic anticoagulant therapy was more frequently used in the NC vs the OCAD group (4.8% vs 1.6%, respectively; P=.02). Recommended ACS evidence-based medications, both in-hospital and at discharge, were less frequently prescribed to patients with NC or NOCAD.
CONCLUSIONS: In a real-world practice of ACS, underutilization of evidence-based medications in patients with NC or NOCAD was observed. Nonetheless, its prognostic significance is still unknown and must be explored in larger patient cohorts.
Sa'ar Minha; Shmuel Gottlieb; Marco A Magalhaes; Natalie Gavrielov-Yusim; Rikardo Krakover; Ilan Goldenberg; Zvi Vered; Alex Blatt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  26     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-08-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  389-93     Citation Subset:  IM    
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