Document Detail

Characteristics of Induced Ventricular Fibrillation Cycle Length in Symptomatic Brugada Syndrome Patients.
MedLine Citation:
PMID:  22251750     Owner:  NLM     Status:  Publisher    
Background: Limited information is available on the ventricular fibrillation (VF) spectrum in Brugada syndrome (BS) patients. We clarified differences in the VF cycle length (CL) using fast-Fourier transformation (FFT) analysis in symptomatic and asymptomatic BS patients. Methods and Results: VF was induced by pacing from the right ventricular (RV) apex and/or RV outflow tract (RVOT) for >8s. A 4096-point FFT analysis of results from 28 male BS patients (51.1±13.7 years old) was performed. Dominant frequency (DF) from phases 1 (4s) to 6 was obtained at 2-s intervals. The average DF from surface and intracardiac electrograms (ECG: DF(ECG); ICE: DF(ICE,), respectively) was compared between symptomatic and asymptomatic patients. Symptomatic patients had a significantly shorter effective refractory period at a CL of 600ms at the RVOT than asymptomatic patients. DF(ECG) significantly increased with phase (5.64±0.32Hz in phase 1 to 6.16±0.52Hz in phase 6) and was significantly higher in symptomatic patients than in asymptomatic patients. DF(ICE) had the same characteristics as DF(ECG). Conclusions: Induced VF in BS patients can be characterized using FFT analysis. Our data support the hypothesis that symptomatic patients have a significantly shorter VF CL than asymptomatic patients.
Atsushi Hiratsuka; Akihiko Shimizu; Takeshi Ueyama; Yasuhiro Yoshiga; Masahiro Doi; Toshihide Ohmiya; Masaaki Yoshida; Masakazu Fukuda; Masunori Matsuzaki
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-17
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  -     ISSN:  1347-4820     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  How many births in sub-Saharan Africa and South Asia will not be attended by a skilled birth attenda...
Next Document:  Natural History of Stent Edge Dissection, Tissue Protrusion and Incomplete Stent Apposition Detectab...