| Characteristics of Induced Ventricular Fibrillation Cycle Length in Symptomatic Brugada Syndrome Patients. | |
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MedLine Citation:
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PMID: 22251750 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: Limited information is available on the ventricular fibrillation (VF) spectrum in Brugada syndrome (BS) patients. We clarified differences in the VF cycle length (CL) using fast-Fourier transformation (FFT) analysis in symptomatic and asymptomatic BS patients. Methods and Results: VF was induced by pacing from the right ventricular (RV) apex and/or RV outflow tract (RVOT) for >8s. A 4096-point FFT analysis of results from 28 male BS patients (51.1±13.7 years old) was performed. Dominant frequency (DF) from phases 1 (4s) to 6 was obtained at 2-s intervals. The average DF from surface and intracardiac electrograms (ECG: DF(ECG); ICE: DF(ICE,), respectively) was compared between symptomatic and asymptomatic patients. Symptomatic patients had a significantly shorter effective refractory period at a CL of 600ms at the RVOT than asymptomatic patients. DF(ECG) significantly increased with phase (5.64±0.32Hz in phase 1 to 6.16±0.52Hz in phase 6) and was significantly higher in symptomatic patients than in asymptomatic patients. DF(ICE) had the same characteristics as DF(ECG). Conclusions: Induced VF in BS patients can be characterized using FFT analysis. Our data support the hypothesis that symptomatic patients have a significantly shorter VF CL than asymptomatic patients. |
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Authors:
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Atsushi Hiratsuka; Akihiko Shimizu; Takeshi Ueyama; Yasuhiro Yoshiga; Masahiro Doi; Toshihide Ohmiya; Masaaki Yoshida; Masakazu Fukuda; Masunori Matsuzaki |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-17 |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: - ISSN: 1347-4820 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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