| Characteristics of 100 consecutive patients presenting with orthostatic hypotension. | |
| | |
MedLine Citation:
|
PMID: 15244385 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To elucidate the demographic and clinical characteristics of a consecutive series of patients who presented for evaluation of orthostatic hypotension. PATIENTS AND METHODS: From January 1, 1997, through September 30, 2001, we assessed retrospectively the demographic and clinical characteristics, antihypertensive medication use, and blood pressure variability in 100 consecutive patients with orthostatic hypotension who underwent 24-hour ambulatory blood pressure monitoring (OH group) and in a convenience sample of 100 age-matched patients who underwent 24-hour ambulatory blood pressure monitoring for evaluation of hypertension (HTN group). RESULTS: The OH group had a mean +/- SD age of 71.6 +/- 9.4 years, and 42% were women. The most common symptoms were light-headedness and weakness. Comorbid conditions included neurologic diseases (38%), preexisting hypertension (36%), hyperlipidemia (31%), cardiac arrhythmias and coronary artery disease (45%), and neoplasm (28%). During ambulatory blood pressure monitoring, postprandial decreases in blood pressure were noted in 83% of the OH group, supine or sleep hypertension in 84%, and noncompensatory heart rate variability in 75%. Findings on autonomic testing were abnormal in 99% of patients, serum creatinine value was increased in 30%, proteinuria was present in 27%, and left ventricular hypertrophy was present in 20%. CONCLUSIONS: Orthostatic hypotension is present in a heterogeneous group of disease states, is usually symptomatic, and is often associated with an abnormal blood pressure profile of reversal of circadian pattern, postprandial hypotension, and noncompensatory heart rate variability. Consequent target organ (kidney) damage can be as frequent as in patients who undergo 24-hour ambulatory blood pressure monitoring for evaluation of hypertension. |
| | |
Authors:
|
A Ahsan Ejaz; William E Haley; Andrew Wasiluk; James F Meschia; Peter M Fitzpatrick |
Related Documents
:
|
19145785 - Home blood pressure telemonitoring improves hypertension control in general practice. t... 3230445 - Utility of occupational blood pressure screening for the detection of potential hyperte... 20562255 - Chronic ambulatory intracardiac pressures and future heart failure events. 3843105 - Blood pressure variations during a working day at age 28: effects of different types of... 15676575 - Intra-abdominal pressure responses of mineworkers to standard loads. 8994945 - An implantable intracardiac accelerometer for monitoring myocardial contractility. the ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Mayo Clinic proceedings. Mayo Clinic Volume: 79 ISSN: 0025-6196 ISO Abbreviation: Mayo Clin. Proc. Publication Date: 2004 Jul |
Date Detail:
|
Created Date: 2004-07-12 Completed Date: 2004-07-27 Revised Date: 2007-10-29 |
Medline Journal Info:
|
Nlm Unique ID: 0405543 Medline TA: Mayo Clin Proc Country: United States |
Other Details:
|
Languages: eng Pagination: 890-4 Citation Subset: AIM; IM |
Affiliation:
|
Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Jacksonville, Fla, USA. ejazaa@medicine.ufl.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Blood Pressure Monitoring, Ambulatory Female Humans Hypertension Hypotension, Orthostatic / drug therapy, physiopathology* Male Middle Aged Retrospective Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Durable responses to thalidomide-based drug therapy for myelofibrosis with myeloid metaplasia.
Next Document: Clinicoradiological features of pulmonary infarctions mimicking lung cancer.