Document Detail

Characteristic changes on brain CT in a case of Leigh encephalopathy with deficiency of pyruvate dehydrogenase.
MedLine Citation:
PMID:  1810165     Owner:  NLM     Status:  MEDLINE    
A girl aged 23 months of Leigh encephalopathy with pyruvate dehydrogenase complex (PDHC) deficiency was reported. Brain CT scan showed atrophy of the frontal and parietal cortex, low density in the midbrain and putamina, and rounded caudatum. CT change was showed from rounded to atrophic caudatum during a three-month period. The rounded caudatum may be an early CT finding in Leigh encephalopathy.
Y Arai; Y Miyasato; H Koide
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Brain & development     Volume:  13     ISSN:  0387-7604     ISO Abbreviation:  Brain Dev.     Publication Date:  1991 Nov 
Date Detail:
Created Date:  1992-05-26     Completed Date:  1992-05-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7909235     Medline TA:  Brain Dev     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  457-8     Citation Subset:  IM    
Division of Child Neurology, Kibou-no-Ie Rehabilitation Center Hospital for the Handicapped, Gunma, Japan.
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MeSH Terms
Brain / enzymology,  radiography*
Leigh Disease / enzymology,  radiography*
Pyruvate Dehydrogenase Complex Deficiency Disease / radiography*
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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