Document Detail


Characterisation of white line degeneration in sheep and evidence for genetic influences on its occurrence.
MedLine Citation:
PMID:  20499170     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Shelly hoof in sheep occurs when the hoof wall becomes detached from the laminar corium; it often then becomes impacted with debris leading to infection, pain and lameness. The problem of shelly hoof is under-reported and is often confused with classical footrot. A study was conducted using data on 9,169 Blackface and Texel sheep from 22 farms in the UK. The aim of the study was to estimate the prevalence of shelly hoof in these breeds, to quantify the genetic basis to shelly hoof, and to describe a pilot trail to characterise the physical properties of horn using Transmission Electron Microscopy (TEM). The results showed that shelly hoof has a high prevalence (47% for Blackface and 24% for Texel ewes) and is under moderate genetic control (h(2) = 0.3). The TEM images showed fragmented dorsal wall horn, microscopic crevices leading deeper into the hoof accompanied by bacteria and other micro-organisms. The invasion of bacteria was facilitated by separation of the cells in a characteristic 'un-zipping' phenomenon, poor attachment of the keratin to the cell membranes, poor cell membrane quality with a 'lace-chain' effect and incomplete keratinisation of the cells.
Authors:
Joanne Conington; Laura Nicoll; Stephen Mitchell; L Bünger
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-05-26
Journal Detail:
Title:  Veterinary research communications     Volume:  34     ISSN:  1573-7446     ISO Abbreviation:  Vet. Res. Commun.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-10     Completed Date:  2010-09-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8100520     Medline TA:  Vet Res Commun     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  481-9     Citation Subset:  IM    
Affiliation:
Sustainable Livestock Systems Group, SAC, R&D Division, West Mains Road, Edinburgh, EH9 3JG, Scotland, UK. jo.conington@sac.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Animals
Female
Foot Diseases / genetics,  veterinary*
Great Britain / epidemiology
Hoof and Claw* / ultrastructure
Lameness, Animal / genetics,  pathology
Microscopy, Electron, Transmission
Prevalence
Sheep / genetics
Sheep Diseases / epidemiology,  genetics*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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