Document Detail


Characterisation of rotavirus causing acute diarrhea in children in Kathmandu, Nepal ; dominance of G12.
MedLine Citation:
PMID:  23038804     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Diarrheal diseases are major problem of developing countries. Though precise data on childhood mortality associated with diarrheal diseases in Nepal is not available, it has been estimated that approximately 25% of child death are associated with diarrheal disease, particularly acute diarrhea. The purpose of this study was to assess the incidence of rotavirus causing acute diarrhea in children under 5 years of age. A total of 525 children with acute diarrhea in a children's hospital of Kathmandu, Nepal were enrolled between April 2011 to September 2011. The incidence of acute diarrhea due to rotavirus was 25.9% (136/525) by ELISA. The percentage of rotavirus infected male were higher 64.5% than female 35.5%. The frequency of rotavirus cases were higher in the children below 2 years of age among which the highest case 80.2% were found in age between 6-24 months (P<0.01). The genotypic characterization by reverse-transcriptase polymerase chain reaction(RT-PCR) revealed that the serotype G12 represented 55.9% in this study associated with P-types either P[6], P[4] or P[8]. Further a total of eight G/P combination were identified, with G12P[6] 46.4% being the most common strain type of rotavirus in Nepal.
Authors:
Shamshul Ansari; Jeevan Bahadur Sherchand; Bharat Mani Pokhrel; Basista Prasad Rijal; Keshav Prasad Parajuli; Shyam Kumar Mishra; Rajan Kumar Dahal; Sovita Shrestha; Sarmila Tandukar
Related Documents :
24811704 - The epidemiology of childhood and adolescent traumatic spinal cord injury in the united...
6915834 - Tinnitus in children with hearing loss.
19146074 - Child abuse and deafness: an overview.
24732564 - Acute coagulopathy in pediatric trauma.
11489054 - Causal explanations, concern and optimism regarding self-injurious behaviour displayed ...
814714 - A study of hl-a types in rh haemolytic disease of the newborn.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-4
Journal Detail:
Title:  Journal of medical microbiology     Volume:  -     ISSN:  1473-5644     ISO Abbreviation:  J. Med. Microbiol.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0224131     Medline TA:  J Med Microbiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
1 Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu;
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Genetic and antigenic characterization of invasive endemic serogroup B Neisseria meningitidis from O...
Next Document:  MaHog1, a Hog1-type MAP kinase gene, contributes to stress tolerance and virulence of the entomopath...