Document Detail

Characterisation of the diol dehydratase pdu operon of Lactobacillus collinoides.
MedLine Citation:
PMID:  12007656     Owner:  NLM     Status:  MEDLINE    
The three genes (pduCDE) encoding the diol dehydratase of Lactobacillus collinoides were sequenced. They exhibited strong identities with the ddrABC and pduCDE genes of Klebsiella oxytoca and Salmonella enterica, respectively. These genes are part of a putative operon with at least four other genes. An eighth open reading frame was identified as homologous to the pocR gene (encoding the operon regulatory protein). Although the enzyme was detected in exponential growth phase, PduCDE activity was increased at the end of exponential phase in presence of 1,2-propanediol.
Nicolas Sauvageot; Cécile Muller; Axel Hartke; Yanick Auffray; Jean-Marie Laplace
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  FEMS microbiology letters     Volume:  209     ISSN:  0378-1097     ISO Abbreviation:  FEMS Microbiol. Lett.     Publication Date:  2002 Mar 
Date Detail:
Created Date:  2002-05-14     Completed Date:  2002-07-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7705721     Medline TA:  FEMS Microbiol Lett     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  69-74     Citation Subset:  IM    
USC INRA de Microbiologie de l'Environnement, Université de Caen, 14032 Caen Cedex, France.
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MeSH Terms
Bacterial Proteins / genetics,  metabolism*
Base Sequence
DNA-Binding Proteins / genetics
Enzyme Induction / drug effects
Genes, Bacterial*
Klebsiella / enzymology,  genetics
Klebsiella pneumoniae / enzymology,  genetics
Lactobacillus / enzymology*
Molecular Sequence Data
Open Reading Frames
Propanediol Dehydratase / genetics,  metabolism*
Propylene Glycol / pharmacology
Reverse Transcriptase Polymerase Chain Reaction
Salmonella enterica / enzymology,  genetics
Species Specificity
Reg. No./Substance:
0/Bacterial Proteins; 0/DNA-Binding Proteins; 0/PocR protein, Salmonella; 0/Trans-Activators; 57-55-6/Propylene Glycol; EC Dehydratase

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