Document Detail

Characterisation of cell movement by impedance measurement on fibroblasts grown on perforated Si-membranes.
MedLine Citation:
PMID:  7495874     Owner:  NLM     Status:  MEDLINE    
Mouse fibroblasts grown on perforated Si-membranes (pore diameter approximately 10 microns have been studied to clarify cell locomotive ability. The cell motility was microscopically monitored by a time-lapse video system and, simultaneously, the impedance of the growing cells was measured every 5 s. The correlations between observed cell activities and measured impedance events are discussed and classified. The method is sensitive and allows discrimination between signals arising from translocation of single cells and those arising from filopodia activities. Both cell and filopodia motion could be detected. Designs of microdevices fabricated in semiconductor technology are presented.
R Hagedorn; G Fuhr; K Lichtwardt-Zinke; E Richter; J Hornung; A Voigt
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biochimica et biophysica acta     Volume:  1269     ISSN:  0006-3002     ISO Abbreviation:  Biochim. Biophys. Acta     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1996-01-17     Completed Date:  1996-01-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0217513     Medline TA:  Biochim Biophys Acta     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  221-32     Citation Subset:  IM    
Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, Institut für Biologie, Lehrstuhl für Membranphysiologie, Germany.
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MeSH Terms
3T3 Cells
Cell Division
Cell Movement*
Cell Size
Fibroblasts / cytology*
Membranes, Artificial*
Microscopy, Electron, Scanning
Reg. No./Substance:
0/Membranes, Artificial; 7440-21-3/Silicon

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