| Changing patterns of bleeding in patients with severe haemophilia A. | |
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MedLine Citation:
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PMID: 19659938 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Previous studies on the pattern of joint bleeding in patients with haemophilia have reported that the knee joint is most frequently affected. Home treatment data reporting bleeding frequency and location collected from 100 patients registered at six haemophilia centres in the UK have been analysed to determine current patterns of bleeding. Bleeding frequency has markedly decreased although bleeding into joints remains the main characteristic of haemophilia. However, the ankle joint has replaced the knee joint as the most common joint affected. Furthermore, it seems that the frequency of knee joint bleeding is also less than the elbow joint suggesting that the traditional pattern of joint bleeding in haemophilia has now changed significantly. |
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Authors:
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D Stephensen; R C Tait; N Brodie; P Collins; R Cheal; D Keeling; K Melton; G Dolan; H Haye; E Hayman; M Winter |
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Publication Detail:
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Type: Journal Article; Multicenter Study Date: 2009-07-29 |
Journal Detail:
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Title: Haemophilia : the official journal of the World Federation of Hemophilia Volume: 15 ISSN: 1365-2516 ISO Abbreviation: Haemophilia Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2010-01-11 Completed Date: 2010-08-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9442916 Medline TA: Haemophilia Country: England |
Other Details:
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Languages: eng Pagination: 1210-4 Citation Subset: IM |
Affiliation:
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Kent Haemophilia Centre, Kent and Canterbury Hospital, Canterbury, UK. david.stephensen@ekht.nhs.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Factors Ankle Joint / physiology* Child Elbow Joint / physiology* Factor VIII / therapeutic use Hemarthrosis / complications*, epidemiology, physiopathology Hemophilia A / complications*, epidemiology, physiopathology Humans Knee Joint / physiology* Male Range of Motion, Articular / physiology Retrospective Studies Self Care Weight-Bearing / physiology* Young Adult |
| Chemical | |
Reg. No./Substance:
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9001-27-8/Factor VIII |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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