Document Detail

Changing incidence of psychotic disorders among the young in Zurich.
MedLine Citation:
PMID:  17630260     Owner:  NLM     Status:  MEDLINE    
There is controversy over whether the incidence rates of schizophrenia and psychotic disorders have changed in recent decades. To detect deviations from trends in incidence, we analysed admission data of patients with an ICD-8/9/10 diagnosis of psychotic disorders in the Canton Zurich / Switzerland, for the period 1977-2005. The data was derived from the central psychiatric register of the Canton Zurich. Ex-post forecasting with ARIMA (Autoregressive Integrated Moving Average) models was used to assess departures from existing trends. In addition, age-period-cohort analysis was applied to determine hidden birth cohort effects. First admission rates of patients with psychotic disorders were constant in men and showed a downward trend in women. However, the rates in the youngest age groups showed a strong increase in the second half of the 1990's. The trend reversal among the youngest age groups coincides with the increased use of cannabis among young Swiss in the 1990's.
Vladeta Ajdacic-Gross; Christoph Lauber; Inge Warnke; Helene Haker; Robin M Murray; Wulf Rössler
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2007-07-16
Journal Detail:
Title:  Schizophrenia research     Volume:  95     ISSN:  0920-9964     ISO Abbreviation:  Schizophr. Res.     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-09-03     Completed Date:  2007-10-24     Revised Date:  2010-09-02    
Medline Journal Info:
Nlm Unique ID:  8804207     Medline TA:  Schizophr Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  9-18     Citation Subset:  IM    
Research Unit for Clinical and Social Psychiatry, Psychiatric University Hospital, Zurich, Switzerland.
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MeSH Terms
Adolescent Psychology*
Cohort Studies
Hospitalization / trends*
International Classification of Diseases / statistics & numerical data
Marijuana Abuse / diagnosis,  epidemiology
Models, Statistical
Patient Admission / trends
Psychotic Disorders / diagnosis,  epidemiology*
Registries / statistics & numerical data
Schizophrenia / diagnosis,  epidemiology*
Sex Distribution
Sex Factors
Switzerland / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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