Document Detail


The changing face of Sheehan's syndrome.
MedLine Citation:
PMID:  20944496     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Postpartum necrosis of the anterior pituitary gland is known as Sheehan's syndrome in honor of Harold Leeming Sheehan who characterized the syndrome as the consequence of ischemia after severe puerperal hemorrhage. With advancements of obstetrical care, Sheehan's syndrome has become uncommon except in developing countries. In many affected women, anterior pituitary dysfunction is not diagnosed for many years after the inciting delivery. This review emphasizes the long period of time that may elapse between the puerperal hemorrhage and the eventual diagnosis of hypopituitarism. The pathophysiology, epidemiology, clinical features and treatment of this disorder are discussed.
Authors:
Alex H Tessnow; Jean D Wilson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  340     ISSN:  1538-2990     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-04     Completed Date:  2010-12-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  402-6     Citation Subset:  AIM; IM    
Affiliation:
Division of Endocrinology and Metabolism, Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas 75390-8857, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Humans
Hypopituitarism / epidemiology,  etiology*,  pathology*,  physiopathology
Middle Aged
Pituitary Gland, Anterior / anatomy & histology,  pathology*,  physiology
Postpartum Hemorrhage*
Pregnancy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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