Document Detail

Changes of ventilation and ventilatory response to hypoxia during the menstrual cycle.
MedLine Citation:
PMID:  6441148     Owner:  NLM     Status:  MEDLINE    
The relationship between change in hypoxic sensitivity in respiration, defined as increment in ventilation per drop of arterial O2 saturation (delta VE/delta SaO2), with the phase change from follicular to luteal and those in resting pulmonary ventilation (VE), mean inspiratory flow (VT/TI), alveolar partial pressures of CO2 and O2 (PACO2 and PAO2, respectively) and body temperature was studied in 10 women. There was a significant relationship between % increase in hypoxic sensitivity and decrement of resting PACO2 that occurred in the luteal phase. However, no significant relationships were observed between change in hypoxic sensitivity and those in the remaining parameters studied. The intersubject variation in % increase in resting VE during the luteal phase was not associated with that in % increase in hypoxic sensitivity. The results indicate that the contribution of increased hypoxic sensitivity to increasing VE during the luteal phase is variable among subjects. Reasons for the increase in hypoxic sensitivity with hypocapnia are discussed.
N Takano
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pflügers Archiv : European journal of physiology     Volume:  402     ISSN:  0031-6768     ISO Abbreviation:  Pflugers Arch.     Publication Date:  1984 Nov 
Date Detail:
Created Date:  1985-03-15     Completed Date:  1985-03-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0154720     Medline TA:  Pflugers Arch     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  312-6     Citation Subset:  IM    
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MeSH Terms
Anoxia / physiopathology*
Carbon Dioxide / blood
Follicular Phase
Inspiratory Capacity
Lung / physiopathology
Luteal Phase
Menstrual Cycle*
Oxygen / blood*
Progesterone / physiology
Tidal Volume
Reg. No./Substance:
124-38-9/Carbon Dioxide; 57-83-0/Progesterone; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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