Document Detail

Changes of urinary iodine excretion of newborns over a period of twenty years.
MedLine Citation:
PMID:  12762639     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The use of iodized salt is not mandatory in Hungary and supply is irregular since decades. The effect of this anomaly was studied on the neonatal urinary iodine excretion over a period of twenty years. DESIGN: Urinary iodine content of 286 newborns' samples was tested in different areas of Hungary in 1980, 1991, and 1999. METHODS: Colorimetric ceric ion-arsenious acid method based on Sandell-Kolthoff reaction was used for determination of urinary iodine content. Fitfy-one samples were excluded from evaluation because of suspicion of iodine contamination. RESULTS: Decreased iodine excretion was demonstrated in different areas and at various times over this period of twenty years in accordance with the results of other (schoolchildren, pregnants) surveys in Hungary. CONCLUSIONS: Iodine deficiency of newborns in these areas changed from year to year, documenting a fluctuating iodine intake. Universal salt iodization should be introduced throughout the country instead of the present "silent iodine prophylaxis" to prevent iodine deficiency, especially in the perinatal period.
F Péter; A Muzsnai; P Bourdoux
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of endocrinological investigation     Volume:  26     ISSN:  0391-4097     ISO Abbreviation:  J. Endocrinol. Invest.     Publication Date:  2003  
Date Detail:
Created Date:  2003-05-23     Completed Date:  2004-01-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7806594     Medline TA:  J Endocrinol Invest     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  39-42     Citation Subset:  IM    
Buda Children's Hospital, Budapest, Hungary.
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MeSH Terms
Deficiency Diseases / epidemiology
Hungary / epidemiology
Infant, Newborn / urine*
Iodine / deficiency,  urine*
Reg. No./Substance:

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