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Changes and significance of serum angiopoietin-2 levels in patients with coronary heart disease.
MedLine Citation:
PMID:  23190218     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Coronary heart disease (CHD) is characterized by inflammatory process and endothelial dysfunction. To investigate angiopoietin-2 (Ang-2) profiles, we evaluated serum Ang-2 levels in different types of CHD in 166 subjects. Ang-2 was measured by enzyme-linked immunosorbent assay. Serum Ang-2 levels were significantly elevated in patients with CHD and gradually increased with advance of CHD. Ang-2 was positively correlated with Gensini scores and hs-CRP. Ang-2 might have potential implication in detecting and monitoring the progression of CHD.
Authors:
Xin Wang; Huijuan Yong; Lin Mi; Yun Bai; Lijun Guo; Wei Gao; Ming Cui; Yongzhen Zhang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals     Volume:  17     ISSN:  1366-5804     ISO Abbreviation:  Biomarkers     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606000     Medline TA:  Biomarkers     Country:  England    
Other Details:
Languages:  eng     Pagination:  745-9     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Peking University Third Hospital and Key Laboratory of Cardiovascular Molecular Biology and Regulatory peptides , Ministry of Health, Beijing , China.
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