| Changes of positron emission tomography in newborn infants at different gestational ages, and neonatal hypoxic-ischemic encephalopathy. | |
| | |
MedLine Citation:
|
PMID: 22264707 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Cerebral glucose metabolism was measured by (18)F-fluorodeoxyglucose position emission tomography in infants at different gestational ages and with neonatal hypoxic-ischemic encephalopathy. Thirty-six preterm and term infants at different gestational ages without brain injury were divided into four subgroups: ≤32 weeks (n = 4), 33-34 weeks (n = 5), 35-36 weeks (n = 12), and ≥37 weeks (n = 15). Twenty-four newborn infants with hypoxic-ischemic encephalopathy were divided into three subgroups: mild (n = 13), moderate (n = 7), and severe (n = 4). Cerebral glucose metabolism manifested a trend toward increase, and the structure of cranial (18)F-fluorodeoxyglucose positron emission tomography images became clear with increased gestational age, especially at ≥37 weeks. Uptakes of (18)F-fluorodeoxyglucose in the ≥37-week group were significantly higher than in the ≤32-week group (P < 0.01). Cerebral glucose metabolism changed significantly in neonatal hypoxic-ischemic encephalopathy, and was either unbalanced bilaterally or relatively low at all sites. Moreover, uptakes of (18)F-fluorodeoxyglucose were significantly lower in severe than in mild and medium hypoxic-ischemic encephalopathy (P < 0.05). Cerebral glucose metabolism, as measured by (18)F-fluorodeoxyglucose positron emission tomography, may prove useful for estimating brain development and injury in newborn infants, and its clinical values need further investigation. |
| | |
Authors:
|
Yuan Shi; Jin-Ning Zhao; Lei Liu; Zhang-Xue Hu; Shi-Fang Tang; Long Chen; Rong-Bin Jin |
Related Documents
:
|
21429057 - Atypical social development in nicu survivors at 12 months. 18771997 - Obstetric management of hepatitis c-positive mothers: analysis of vertical transmission... 9144377 - Function and phenotype of immature cd4+ lymphocytes in healthy infants and early lympho... 9384297 - Rapid diagnosis of pertussis in young infants: comparison of culture, pcr, and infant's... 23445737 - Influence and mechanisms of maternal and infant diets on the development of childhood a... 20689747 - Back to the future: studying cholera pathogenesis using infant rabbits. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Pediatric neurology Volume: 46 ISSN: 1873-5150 ISO Abbreviation: Pediatr. Neurol. Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-01-23 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8508183 Medline TA: Pediatr Neurol Country: United States |
Other Details:
|
Languages: eng Pagination: 116-23 Citation Subset: IM |
Copyright Information:
|
Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Pediatrics, Daping Hospital, Third Military Medical University, Chongqing, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Neonatal seizures: treatment practices among term and preterm infants.
Next Document: Reactivation of varicella presenting as pseudotumor cerebri: three cases and a review of the literat...