Document Detail


Changes of myelinated nerve and myelin basic protein expression in rats' periodontal ligaments after experimental tooth movement.
MedLine Citation:
PMID:  23195367     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
INTRODUCTION: Information about the effect of tooth movement on the myelinated nerve in the periodontal ligament is limited. In this study, we aimed to investigate what responses of the periodontal myelinated nerve can be evoked during experimental tooth movement.
METHODS: In experimental-I group, the maxillary left and mandibular right third molars were moved distally. In experimental-II group, the maxillary left third molar but not the right one was moved, and the bilateral mandibular third molars were extracted. The ultrastructures of the myelinated nerve in the periodontal ligament of the bilateral maxillary third molars were observed under a transmission electron microscope. The expression of myelin basic protein was evaluated by immunohistochemistry.
RESULTS: Degenerative ultrastructural changes of the myelinated nerve in the periodontal ligament were noticed mainly in the myelin sheath; these were observed earlier and were recoverable in the experimental-I group. In contrast, the ultrastructural changes of the myelinated nerve occurred mainly in the axons, were observed later, and were unrecoverable in the experimental-II group. A concomitant decrease of myelin basic protein expression was observed in both groups.
CONCLUSIONS: Both experimental tooth movement and occlusal changes accompanying it caused changes of the myelinated nerve in the periodontal ligament.
Authors:
Lei Lu; Jing-Hui Huang; Shi-Bin Yu; Xiao-Dong Liu; Yuan Zhang; Xu Zhang; Zhong-Ying Qiu; Mei-Qing Wang
Related Documents :
23247327 - Impact of nutrition on muscle mass, strength, and performance in older adults.
7275857 - Porcine stress syndrome and postmortem muscle characteristics of two purebreds and thre...
23707407 - Pleiad/simc1/c5orf25, a novel autolysis regulator for a skeletal-muscle-specific calpai...
24180497 - Reactive oxygen species regulation of autophagy in skeletal muscles.
9331927 - Expression of corticotropin-releasing factor in the peripheral nervous system of the rat.
20707637 - Addition of an anabolic steroid to strength training promotes muscle strength in the no...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics     Volume:  142     ISSN:  1097-6752     ISO Abbreviation:  Am J Orthod Dentofacial Orthop     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8610224     Medline TA:  Am J Orthod Dentofacial Orthop     Country:  United States    
Other Details:
Languages:  eng     Pagination:  814-24     Citation Subset:  D; IM    
Copyright Information:
Copyright © 2012 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.
Affiliation:
Postgraduate student, Department of Oral Anatomy and Physiology and TMD, School of Stomatology, Fourth Military Medical University, Xi'an, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Imaging software accuracy for 3-dimensional analysis of the upper airway.
Next Document:  Three-dimensional assessment of transverse skeletal changes after surgically assisted rapid maxillar...