Document Detail


Changes in venous blood content from active and inactive hindlimb during isotonic exercise.
MedLine Citation:
PMID:  4039267     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Venous blood samples were obtained from either exercising (n = 9) or nonexercising (n = 8) hindlimb during a progressive isotonic exercise in rabbits anesthetized with urethane and chloralose. Each experimental session consisted of 5-min nonexercise periods alternated with 6-min exercise periods, followed by a 10-min postexercise period. During each exercise period, stimulation of the distal stump of the right sciatic nerve at 1 Hz induced plantar flexions which lifted loads comparable to 2, 5, 8, 30, or 50% of an afterload at which only an isometric tension developed. Free-flowing venous blood samples were obtained before the first exercise period, during the last minute of each exercise period, and 10 min following the last exercise session. Increases in [Na+], [K+] and lactate concentration were obtained in blood from active limbs. Only lactate concentration increased in blood from nonexercising limbs, while [K+] decreased slightly. Inferences concerning the vascular volume response to this protocol would be quite different depending on the blood sampling site. Changes in blood from inactive tissue, further, may indicate only saturation of homeostatic mechanisms which normally compensate for vascular volume alterations initiated in active tissue.
Authors:
C J Gaebelein; C M Ladd; A M Moudy
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  European journal of applied physiology and occupational physiology     Volume:  53     ISSN:  0301-5548     ISO Abbreviation:  Eur J Appl Physiol Occup Physiol     Publication Date:  1985  
Date Detail:
Created Date:  1985-06-17     Completed Date:  1985-06-17     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0410266     Medline TA:  Eur J Appl Physiol Occup Physiol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  372-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Chemical Analysis*
Chlorides / blood
Hemoglobins / analysis
Hindlimb
Lactates / blood
Male
Muscle Contraction*
Potassium / blood
Rabbits
Sodium / blood
Veins
Grant Support
ID/Acronym/Agency:
HL26895/HL/NHLBI NIH HHS; RR05388/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Chlorides; 0/Hemoglobins; 0/Lactates; 7440-09-7/Potassium; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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