Document Detail

Changes in the sympathetic skin response after thoracoscopic sympathectomy in patients with primary palmar hyperhidrosis.
MedLine Citation:
PMID:  15978496     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To investigate whether thoracic sympathectomy induced any change in the pattern of abnormalities or in the waveform of the sudomotor skin response (SSR) in patients with primary palmar hyperhidrosis (PPH). METHODS: We recorded the SSR to median nerve electrical stimuli before and after bilateral thoracoscopic sympathectomy in 27 patients with PPH. We analyzed the changes in amplitude, type of waveform and pattern of abnormality. RESULTS: All patients reported symptomatic improvement. The amplitude of the SSR decreased significantly in patients examined within 1 year after surgery, but was not different in patients examined after 1 year. The number of abnormally enhanced responses reduced after surgery, but there was no significant change in the number of patients with enhanced excitability recovery or with double-peak responses to single stimuli. There was a significant increase in the number of SSRs with a predominantly negative waveform after surgery. CONCLUSIONS: The persistence of SSR abnormalities after surgery suggests that the central nervous system dysfunction is not modified by sympathectomy. The change of the waveform to predominantly negative type after surgery could be the consequence of the decrease in the production of sweating. SIGNIFICANCE: Our results show the effects of sympathectomy on the SSR and on its abnormal patterns in patients with PPH.
A Lladó; L León; J Valls-Solé; P Mena; M A Callejas; J M Peri
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article     Date:  2005-03-29
Journal Detail:
Title:  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology     Volume:  116     ISSN:  1388-2457     ISO Abbreviation:  Clin Neurophysiol     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-06-27     Completed Date:  2005-08-09     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  100883319     Medline TA:  Clin Neurophysiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1348-54     Citation Subset:  IM    
Neurology Department, Hospital Clínic, University of Barcelona, Institut d'Investigació Biomèdica August Pi i Sunyer, Barcelona, Spain.
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MeSH Terms
Chi-Square Distribution
Electric Stimulation / methods
Follow-Up Studies
Hand / physiopathology,  radiation effects
Hyperhidrosis / physiopathology,  surgery*
Median Nerve / physiopathology*,  radiation effects
Pain Measurement / methods
Retrospective Studies
Skin Physiological Phenomena*
Sympathectomy / methods*
Thoracoscopy / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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