Document Detail

Changes in stenosis resistance and myocardial blood flow after a brief coronary occlusion in the dog.
MedLine Citation:
PMID:  6650224     Owner:  NLM     Status:  MEDLINE    
Stress-induced changes in the resistance due to coronary arterial stenosis of a fixed diameter and in the myocardial blood flow distal to the stenosis were investigated in the open-chest dog. Myocardial blood flow in the inner and outer third of the left ventricular wall was continuously measured with heated cross-thermocouples. The circumflex coronary artery was constricted with a thick string so that myocardial reactive hyperemia was nearly eliminated. Without constriction, a 15-second occlusion of the artery produced no significant changes in the resistance of large coronary arteries. On the contrary, in the presence of coronary constriction, a brief coronary occlusion caused a sustained decrease in distal coronary pressure and subendocardial myocardial flow during reactive hyperemia, while coronary flow returned quickly to the pre-occlusion level with significant reactive hyperemia of subepicardial flow. This change resulted in a long-lasting increase in the stenosis resistance. These results suggest that stenosis resistance changes dynamically, resulting in additional myocardial ischemia especially in the subendocardial myocardial layers.
D Saito; Y Abe; K Takeda; T Hyodo; H Tani; S Ohnishi; S Haraoka; H Nagashima
Related Documents :
6791274 - Haemodynamic effects of nitroglycerin in comparison with preload and sodium nitroprussi...
9201624 - Beta-adrenergic receptor signalling in stunned myocardium of conscious pigs.
9253854 - Adenosine in the mammalian heart: nothing to get excited about.
11916774 - The cardiac effects of intracoronary angiotensin ii infusion.
17226084 - Variation in left atrial transmural wall thickness at sites commonly targeted for ablat...
9852904 - Ischemic preconditioning in immature myocardium.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta medica Okayama     Volume:  37     ISSN:  0386-300X     ISO Abbreviation:  Acta Med. Okayama     Publication Date:  1983 Oct 
Date Detail:
Created Date:  1984-01-07     Completed Date:  1984-01-07     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0417611     Medline TA:  Acta Med Okayama     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  423-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood Pressure
Coronary Circulation*
Coronary Disease / physiopathology*
Coronary Vessels
Time Factors
Vascular Resistance*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Aggressive behaviour in a psychiatric observation ward.
Next Document:  Deviation of somatosensory evoked potential and lateral dominance of spike activity in iron-induced ...