Document Detail

Changes in skeletal mineral in patients on prolonged maintenance dialysis.
MedLine Citation:
PMID:  4357138     Owner:  NLM     Status:  MEDLINE    
The measurement of bone loss in patients undergoing maintenance dialysis over a period of two and a half years is reported. The tendency to lose bone is a likely event in renal failure, but depends more on the individual patient than on the type of dialysis used, provided that steps are taken to prevent avoidable calcium loss during dialysis. Vitamin D therapy was an important factor in preventing bone loss in some cases. The tendency to lose bone more readily when both kidneys were absent may have reflected a deficiency of 1-25 dihydrocholecalciferol. On the other hand, bone loss was also observed in transplanted patients. The need to measure bone loss at regular intervals once renal failure has been diagnosed is stressed.
P J Atkinson; D A Hancock; V N Acharya; F M Parsons; E A Proctor; G W Reed
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  4     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1973 Dec 
Date Detail:
Created Date:  1974-01-31     Completed Date:  1974-01-31     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  519-22     Citation Subset:  AIM; IM    
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MeSH Terms
Alkaline Phosphatase / blood
Bone Resorption / etiology*
Calcium / blood,  metabolism
Cholecalciferol / metabolism
Kidney Transplantation
Middle Aged
Peritoneal Dialysis*
Phosphorus / blood
Renal Dialysis*
Urea / blood
Vitamin D / therapeutic use*
Reg. No./Substance:
1406-16-2/Vitamin D; 57-13-6/Urea; 67-97-0/Cholecalciferol; 7440-70-2/Calcium; 7723-14-0/Phosphorus; EC Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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