| Changes in sexual problems over time in women with and without early-stage breast cancer. | |
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MedLine Citation:
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PMID: 20461020 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: We aimed to evaluate whether age-matched women with and without early-stage breast cancer differentially experience sexual problems over time and whether changes in patients' problems differ by type of surgical procedure. METHODS: We conducted four interviews (4-6 wk, 6 mo, and 1 and 2 y) after tumor resection (patients) or after a negative/benign screening mammogram (controls). Mixed-effects models with repeated ordinal measurements tested the effects of time and diagnostic group (stages 0, I, and IIA vs controls) and, for patients, the effects of time and type of surgical procedure (mastectomy vs lumpectomy) using a newly developed nine-item sexual-problem measure. Two-sided P values < 0.05 were considered significant. RESULTS: Using data from 1,033 women (17.3% stage 0, 33.4% stage I/IIA, and 49.3% controls; mean age, 57.1 y; 23.1% nonwhite; 64.7% married), two factors measuring problems with sexual attractiveness and sexual interest/enjoyment emerged in exploratory factor analysis (alpha > or = 0.74 for each subscale and the nine-item measure). Patients and controls reported few sexual problems on average, but controls were more likely to report sexual problems on the nine-item measure over time and stage I patients were less likely to report problems with sexual attractiveness over time (each P < 0.05) compared with at baseline. Patients who underwent mastectomy (35.7%) were 2.7 times more likely to report sexual problems on the nine-item measure at 2-year follow-up compared with baseline (P = 0.0339). CONCLUSIONS: Patients and controls experienced few sexual problems over time, and in fact, controls were more likely to report sexual problems at subsequent interviews, whereas patients were not. |
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Authors:
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Maria Pérez; Ying Liu; Mario Schootman; Rebecca L Aft; Kenneth B Schechtman; William E Gillanders; Donna B Jeffe |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Menopause (New York, N.Y.) Volume: 17 ISSN: 1530-0374 ISO Abbreviation: Menopause Publication Date: 2010 Sep-Oct |
Date Detail:
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Created Date: 2010-09-14 Completed Date: 2011-01-06 Revised Date: 2011-11-10 |
Medline Journal Info:
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Nlm Unique ID: 9433353 Medline TA: Menopause Country: United States |
Other Details:
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Languages: eng Pagination: 924-37 Citation Subset: IM |
Affiliation:
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Division of Health Behavior Research, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63108, USA. mperez@dom.wustl.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Breast Neoplasms / pathology*, psychology*, surgery Case-Control Studies Female Follow-Up Studies Humans Incidence Interviews as Topic Mammography / psychology Mastectomy / psychology Middle Aged Neoplasm Staging Quality of Life* Sexual Dysfunctions, Psychological / epidemiology* Survivors |
| Grant Support | |
ID/Acronym/Agency:
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P30 CA91842/CA/NCI NIH HHS; R01 CA102777-05/CA/NCI NIH HHS; R01CA102777/CA/NCI NIH HHS |
| Comments/Corrections | |
Comment In:
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Menopause. 2010 Sep-Oct;17(5):894-5
[PMID:
20700064
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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