Document Detail


Changes in serum uric acid concentrations during normal pregnancy.
MedLine Citation:
PMID:  6696858     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Serial changes in serum uric acid concentrations have been studied in a group of healthy women before conception, at regular intervals throughout pregnancy and finally 12 weeks after delivery. Compared with pre-pregnancy values uric acid concentrations decreased significantly by 8 weeks gestation and this reduced level was maintained until about 24 weeks. Thereafter the concentrations increased such that by term they were greater than the pre-pregnancy values in the majority of patients and remained elevated until at least 12 weeks after delivery. If clinical management during the second half of pregnancy is to be based on increases in serum uric acid concentrations then such increases will have to be carefully interpreted against the background of rising concentrations which occur as part of the physiological response to normal pregnancy.
Authors:
T Lind; K A Godfrey; H Otun; P R Philips
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  91     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1984 Feb 
Date Detail:
Created Date:  1984-04-03     Completed Date:  1984-04-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  128-32     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Humans
Postpartum Period
Pregnancy*
Time Factors
Uric Acid / blood*
Chemical
Reg. No./Substance:
69-93-2/Uric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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