Document Detail


Changes in rosacea comorbidities and treatment utilization over time.
MedLine Citation:
PMID:  21061763     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Rosacea is a chronic skin condition that requires lifelong treatment. Given the rise in antibiotic-resistant bacteria, many physicians are re-evaluating their use of antibiotics for long-term treatment of rosacea.
PURPOSE: To examine trends in the treatment of rosacea and the comorbidities associated with this skin condition.
METHODS: From 2002-2006, the National Ambulatory Medical Care Survey queried drug mentions at rosacea visits and coexisting diagnoses. Prescribing patterns of dermatologists were compared to other physicians' patterns.
RESULTS: Ten million physician visits had the diagnosis of rosacea; 74 percent were associated with co-morbidities. Metronidazole, tetracyclines, azelaic acid and sodium sulfacetamide were the top medications mentioned at rosacea visits. Prescriptions increased for azelaic acid and decreased for sodium sulfacetamide. Dermatologists decreased their prescribing of systemic medications.
CONCLUSION: Dermatologists are reducing their use of systemic antibiotics for rosacea and turning to therapies, such as azelaic acid, that do not have potential to induce bacterial resistance.
Authors:
Brad A Yentzer; Alan B Fleischer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of drugs in dermatology : JDD     Volume:  9     ISSN:  1545-9616     ISO Abbreviation:  J Drugs Dermatol     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-10     Completed Date:  2010-12-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101160020     Medline TA:  J Drugs Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1402-6     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1071, USA.
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / administration & dosage
Dermatologic Agents / therapeutic use
Drug Utilization / statistics & numerical data
Female
Humans
Male
Physician's Practice Patterns*
Rosacea / complications,  drug therapy*
Skin Diseases / complications
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Dermatologic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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