Document Detail

Changes in the retrobulbar arterial circulation after decrease of elevated intraocular pressue in patients with primary open angle glaucoma.
MedLine Citation:
PMID:  22338465     Owner:  NLM     Status:  In-Process    
INTRODUCTION: An altered perfusion of the optic nerve head has been proposed as a pathogenic factor in glaucoma.
OBJECTIVE: To evaluate changes of haemodynamic parameters in the retrobulbar arterial circulation after a decrease of elevated intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG).
METHODS: Twenty-six patients were examined, 14 men and 12 women, 21 up to 50 years old and 5 below, all with previously diagnosed and treated POAG, and all examined at the Eye Clinic, Clinical Centre of Serbia. IOP was measured both with a Goldmann aplanation tonometer and dynamic contour tonometer. Central corneal thickness was measured with ultrasound pachymeter. Imaging of the retrobulbar arterial circulation by colour Doppler was performed at the Neurology Clinic, Clinical Centre of Serbia. It involved measuring of haemodynamic parameters of the ophthalmic artery, central retinal artery, and posterior ciliary arteries. Peak systolic velocity (PSV) and end-diastolic velocity (EDV) were measured, and resistive index (RI) and pulsatility index (PI) were calculated.
RESULTS: Haemodynamic arterial parameters PSV and EDV in the ophthalmic and central retinal artery after decrease of IOP were lower, while RI and PI were higher. In the posterior ciliary arteries PSV, EDV and PI were lower, and RI was higher.
CONCLUSION: Changes of the retrobulbar arterial circulation after elevated LOP in POAG patients are important for approach and treatment, while the role of vascular factors in the supplement of the optic disc neuroretinal rim could be a key for progression backlash of glaucoma and the radix of neuroprotection.
Ivan Marjanović; Ana Sundić; Milija Mijajlović; Nadezda Covicković-Sternić; Djordje Kontić; Paraskeva Hentova-Senćanić; Vujica Marković; Marija Bozić; Miroslav Knezević
Related Documents :
3438715 - The internal mammary artery as subclavian artery substitute in repair of coarctation of...
16295075 - The roentgen diagnosis of a case of takayasu's arteriopathy.
3027815 - Prediction of subclavian vein location using plain chest radiography.
20732535 - Massive coronary subclavian steal syndrome.
16159835 - Survival benefit of exclusive use of in situ arterial conduits over combined use of art...
7838805 - Acute pseudoaneurysm formation complicating balloon dilation of native coarctation: tre...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Srpski arhiv za celokupno lekarstvo     Volume:  139     ISSN:  0370-8179     ISO Abbreviation:  Srp Arh Celok Lek     Publication Date:    2011 Nov-Dec
Date Detail:
Created Date:  2012-02-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0027440     Medline TA:  Srp Arh Celok Lek     Country:  Serbia    
Other Details:
Languages:  eng     Pagination:  718-21     Citation Subset:  IM    
Clinic of Eye Diseases, Clinical Centre of Serbia, Pasterova 2 St, 11000 Belgrade.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Classical presentation of Darier's disease: a rare disorder of keratinisation.
Next Document:  [Influence of different bonding agents on marginal sealing quality of amalgam restorations].