Document Detail


Changes in resting metabolic rate and substrate oxidation after 16 months of exercise training in overweight adults.
MedLine Citation:
PMID:  18272935     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To determine whether 16 months of moderate-intensity exercise training changes resting metabolic rate (RMR) and substrate oxidation in overweight young adults. METHODS: Participants were randomly assigned to nonexercise control (CON, 18 women, 15 men) or exercise (EX, 25 women, 16 men) groups. EX performed supervised and verified exercise 3-5 d/wk, 20-45 min/session, at 60-75% of heart-rate reserve. Body mass and composition, maximal oxygen consumption (VO2max), RMR, and resting substrate oxidation were assessed at baseline and after 9 and 16 months of training. RESULTS: EX men had significant decreases from baseline to 9 months in body mass (94.6+/-12.4 to 89.2+/-9.5 kg) and percent fat (28.3+/-4.6 to 24.5+/-3.9). CON women had significant increases in body mass (80.2+/-8.1 to 83.2+/-9.2 kg) from baseline to 16 months. VO2max increased significantly from baseline to 9 months in the EX men (3.67+/-0.62 to 4.34+/-0.58 L/min) and EX women (2.53+/-0.32 to 3.03+/-0.42 L/min). RMR increased from baseline to 9 months in EX women (1,583+/-221 to 1,692+/-230 kcal/d) and EX men (1,995+/-184 to 2,025+/-209 kcal/d). There were no significant differences within genders for either EX or CON in fat or carbohydrate oxidation. Fat oxidation was significantly higher for women than for men at 9 months in both CON and EX groups. CONCLUSIONS: Regular moderate-intensity exercise in healthy, previously sedentary overweight and obese adults increases RMR but does not alter resting substrate oxidation. Women tend to have higher RMR and greater fat oxidation, when expressed per kilogram fat-free mass, than men.
Authors:
Jeffrey A Potteiger; Erik P Kirk; Dennis J Jacobsen; Joseph E Donnelly
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  International journal of sport nutrition and exercise metabolism     Volume:  18     ISSN:  1526-484X     ISO Abbreviation:  Int J Sport Nutr Exerc Metab     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-14     Completed Date:  2008-04-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100939812     Medline TA:  Int J Sport Nutr Exerc Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  79-95     Citation Subset:  IM    
Affiliation:
Dept. of Kinesiology and Health, Miami University, Oxford, OH 45056-3491, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Basal Metabolism / physiology*
Body Composition / physiology
Energy Metabolism / physiology*
Exercise / physiology*
Female
Humans
Male
Overweight / metabolism*
Oxidation-Reduction
Oxygen Consumption
Respiration
Grant Support
ID/Acronym/Agency:
DK49181/DK/NIDDK NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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