Document Detail


Changes in the regression slope correlating between urinary contents of alpha-1-microglobulin and ulinastatin and its relation to severity in mood disorders.
MedLine Citation:
PMID:  11882184     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
With mood disorders, clinical portrayals alone do not always reflect the exact state and progress of the disease. The present study attempted to evaluate whether changes in regression slope correlating between urinary contents of alpha-1-microglobulin and ulinastatin provided objective information on the severity of mood disorders, based on our previous findings that the regression slope was more steeply inclined in patients with mood disorders than in age-matched healthy subjects. As a result, a close association between scores of the Hamilton Rating Scale for Depression and the regression slopes was found: the more inclined the slope, the greater the severity of symptoms of depression. These results suggest that changes in the slope of the regression plot correlating between urinary contents of alpha 1 M and UT may afford a useful objective index when monitoring the state of patients with mood disorders.
Authors:
T Shikimi; J Uegaki; T Inagaki; S Mitsuoka
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nursing & health sciences     Volume:  3     ISSN:  1441-0745     ISO Abbreviation:  Nurs Health Sci     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2002-03-07     Completed Date:  2002-09-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100891857     Medline TA:  Nurs Health Sci     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  95-100     Citation Subset:  N    
Affiliation:
Department of Fundamental Nursing, School of Nursing, Shimane Medical University, Izumo, Shimane 693-8501, Japan. tshikimi@shimane-med.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Alpha-Globulins / metabolism,  urine*
Biological Markers / analysis
Female
Glycoproteins / metabolism,  urine*
Humans
Middle Aged
Mood Disorders / diagnosis*,  urine
Sampling Studies
Sensitivity and Specificity
Severity of Illness Index
Chemical
Reg. No./Substance:
0/Alpha-Globulins; 0/Biological Markers; 0/Glycoproteins; 0/alpha-1-microglobulin; 80449-32-7/urinastatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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