Document Detail

Changes in protease inhibitors after acute myocardial infarction.
MedLine Citation:
PMID:  61974     Owner:  NLM     Status:  MEDLINE    
Plasma levels of fibrinogen, alpha1-antitrypsin, alpha2-macroglobulin, antithrombin III, and C1 inactivator were measured serially for 10 days in 11 patients after acute myocardial infarction. Both fibrinogen and alpha1-antitrypsin rose markedly to reach peak levels 5-7 days after infarction while C1 inactivator levels rose slowly with the highest observed mean level on the 10th postinfarction day. Neither antithrombin III nor alpha2-macroglobulin changed significantly after myocardial infarction. No relationship between C1 inactivator levels and either fibrinogen or alpha1-antitrypsin was found in a study of 30 patients with a variety of disorders while fibrinogen and alpha1-antitrypsin levels were significantly correlated.
J A Rennie; G P Crawford; D Ogston
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  29     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1976 Jul 
Date Detail:
Created Date:  1976-12-23     Completed Date:  1976-12-23     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  639-41     Citation Subset:  AIM; IM    
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MeSH Terms
Antithrombins / analysis
Complement C1 Inactivator Proteins
Fibrinogen / analysis
Middle Aged
Myocardial Infarction / blood*,  enzymology
Protease Inhibitors*
alpha 1-Antitrypsin / analysis
alpha-Macroglobulins / analysis
Reg. No./Substance:
0/Antithrombins; 0/Complement C1 Inactivator Proteins; 0/Protease Inhibitors; 0/alpha 1-Antitrypsin; 0/alpha-Macroglobulins; 9001-32-5/Fibrinogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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