Document Detail

Changes in plasma non esterified fatty acids and serum glycerol in pregnancy.
MedLine Citation:
PMID:  1138836     Owner:  NLM     Status:  MEDLINE    
Changes in plasma nonesterified fatty acids (NEFA) and serum glycerol in pregnancy were examined in a semi-serial study of 85 women. A preliminary study showed that it was almost impossible to achieve standardized conditions for sampling, and the compromise of taking a single venous sample without stasis, after 30 minutes rest and about 12 hours fasting, was adopted. Although there were large individual variations the patterns of change were, in general, the same for NEFA and glycereo although the two were not closely correlated. There was no +convincing change before 30 weeks of pregnancy but both increased in the last ten weeks, fell sharply in the first week post partum, and then rose again to late pregnancy levels by 6 weeks post partum before falling to non-pregnant levels by between 3 and 6 months post partum. Those patterns of change are in broad accordin with changes of fat storage and lipolysis associated with the reporoductive cycle. Changes in the patterms of NEFA were triviax the only significant alteration was a small rise in the proportion of C16:0 (palmitic) in late pregnancy.
R G McDonald-Gibson; M Young; F E Hytten
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  82     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1975 Jun 
Date Detail:
Created Date:  1975-09-24     Completed Date:  1975-09-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  460-6     Citation Subset:  AIM; IM    
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MeSH Terms
Chromatography, Gas
Fatty Acids, Nonesterified / blood*
Glycerol / blood*
Oleic Acids / blood
Palmitic Acids / blood
Time Factors
Reg. No./Substance:
0/Fatty Acids, Nonesterified; 0/Oleic Acids; 0/Palmitic Acids; 56-81-5/Glycerol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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