| Changes in plasma gangliosides in relation to tumor growth and their tumor-enhancing effect. | |
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MedLine Citation:
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PMID: 3346109 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Gangliosides in the plasma of Ehrlich ascites tumor-bearing mice showed changes, both quantitative and qualitative, with progress of tumor. Quantitative changes assessed by chemical estimation indicated a gradual increase of gangliosides up to day 6 of tumor growth followed by a decline leading to a level below the normal by day 12. Qualitative changes studied by thin-layer chromatography indicated appearance of new gangliosides in the plasma of tumor-bearing mice, which were absent from normal plasma. One of these gangliosides appears to be of tumor-cell origin. Gangliosides obtained from tumor-bearing mouse plasma enhanced tumor growth when adoptively transferred with tumor cells into normal mice. |
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Authors:
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S Saha; U Chattopadhyay |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of cancer. Journal international du cancer Volume: 41 ISSN: 0020-7136 ISO Abbreviation: Int. J. Cancer Publication Date: 1988 Mar |
Date Detail:
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Created Date: 1988-04-20 Completed Date: 1988-04-20 Revised Date: 2007-07-24 |
Medline Journal Info:
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Nlm Unique ID: 0042124 Medline TA: Int J Cancer Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 432-5 Citation Subset: IM |
Affiliation:
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Department of Tumor Immunobiology, Chittaranjan National Cancer Research Centre, Calcutta, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Carcinoma, Ehrlich Tumor / blood, immunology* Chromatography, Thin Layer Gangliosides / blood*, immunology Immunization, Passive Male Mice Neoplasm Transplantation |
| Chemical | |
Reg. No./Substance:
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0/Gangliosides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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