Document Detail


Changes in perifollicular vascularity after administration of human chorionic gonadotropin measured by quantitative three-dimensional power Doppler ultrasound.
MedLine Citation:
PMID:  20517679     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To determine the perifollicular vascular network and blood flow changes of the dominant preovulatory follicle using quantitative three-dimensional (3D) power Doppler analysis. METHODS: A total of 21 cycles were studied in spontaneously ovulating women who underwent folliculometry and 3D power Doppler angiography of perifollicular blood flow of the dominant preovulatory follicle on the day of human chorionic gonadotropin (hCG) administration and 24 h after it. RESULTS: At 24 h after the administration of hCG, increases were found in the area inside the biggest follicular circumference (8.48 +/- 1.73 cm(2) vs. 9.30 +/- 1.64 cm(2)), in the percentage of vessel volume inside the perifollicular capsule (3.58 +/- 3.65% vs. 7.76 +/- 10.13%) and in total perifollicular blood volume (931.33 +/- 1084.60 vs. 3486.00 +/- 7272.34). Moreover, the rearrangement in blood volume distribution resulted in equalization of the contribution of each feeding vessel to total perifollicular blood flow. A more uniform vascular network resulting in decreased dominance of a single feeding vessel in total inflow was found (50.50 +/- 28.18% vs. 29.05 +/- 14.14%). CONCLUSION: After the administration of hCG there was a visible increase in perifollicular capillary network volume, relative volume of blood, and balancing of blood inflow of each feeding vessel of the perifollicular circulation.
Authors:
Veljko Vlaisavljević; Elko Borko; Branko Radaković; Damjan Zazula; Marko Dosen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Wiener klinische Wochenschrift     Volume:  122 Suppl 2     ISSN:  1613-7671     ISO Abbreviation:  Wien. Klin. Wochenschr.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-06-02     Completed Date:  2010-10-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  21620870R     Medline TA:  Wien Klin Wochenschr     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  85-90     Citation Subset:  IM    
Affiliation:
Department of Reproductive Medicine and Gynecologic Endocrinology, University Clinical Center Maribor, Maribor, Slovenia. vlai@ukc-mb.si
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Volume / drug effects
Capillaries / drug effects,  ultrasonography
Chorionic Gonadotropin / administration & dosage*
Female
Fertilization in Vitro
Follicular Phase / drug effects
Humans
Image Processing, Computer-Assisted / methods*
Imaging, Three-Dimensional / methods*
Neural Networks (Computer)
Ovarian Follicle / blood supply*,  ultrasonography
Prospective Studies
Regional Blood Flow / drug effects
Sperm Injections, Intracytoplasmic
Ultrasonography, Doppler, Color / methods*
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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