Document Detail

Changes in oxygenation and compliance as related to body position in acute lung injury.
MedLine Citation:
PMID:  8955244     Owner:  NLM     Status:  MEDLINE    
Body positioning during mechanical ventilation for acute lung injury has not been studied in a detailed manner. We evaluated the relationship between oxygenation, compliance, and body position during mechanical ventilation of patients with acute lung injury (ALI). Sixteen patients on mechanical ventilation with a diagnosis of ALI (partial pressure of oxygen/fraction of inspired oxygen <300 and no clinical evidence of congestive heart failure) were prospectively studied. Each patient was placed in a supine position followed by a 30 degrees head elevation and a 45 degrees head elevation. Data obtained in each position (after a 45-60 minute equilibration time) included static pulmonary compliance and partial pressure of oxygen from arterial blood gas sampling. Oxygenation is not improved and compliance is adversely affected by upright body positioning as compared to the supine position in patients receiving mechanical ventilation for ALI.
E Bittner; A Chendrasekhar; S Pillai; G A Timberlake
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The American surgeon     Volume:  62     ISSN:  0003-1348     ISO Abbreviation:  Am Surg     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-01-07     Completed Date:  1997-01-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370522     Medline TA:  Am Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1038-41     Citation Subset:  IM    
Department of Surgery, West Virginia University School of Medicine, Morgantown, USA.
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MeSH Terms
Aged, 80 and over
Lung Compliance
Lung Injury*
Middle Aged
Oxygen / blood*
Oxygen Consumption / physiology
Positive-Pressure Respiration
Posture / physiology*
Prospective Studies
Respiration, Artificial*
Reg. No./Substance:

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