Document Detail

Changes in metabolic syndrome and its components with lifestyle modification in Japanese men.
MedLine Citation:
PMID:  20154429     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Changes in metabolic syndrome and its components with lifestyle modification were evaluated in Japanese men. METHODS: We used data for 160 Japanese men (45.6+/-8.8 years) with a 1-year follow up. Anthropometric, blood examination and blood pressure measurements were evaluated. Metabolic syndrome was defined by using a criterion in Japan. All subjects were given instructions by well-trained medical staff on how to change their lifestyle. RESULTS: With a 1-year follow-up, anthropometric parameters, blood pressure (BP), triglyceride and HDL cholesterol were significantly improved and the prevalence of metabolic syndrome was significantly reduced. The number of subjects with abdominal obesity at baseline and at follow-up was higher (81 men) than that of subjects with other components at baseline and at follow-up. Parameters at baseline were significantly correlated with changes in parameters for one year. With lifestyle modification, the level of 163 mmHg in systolic BP (SBP), 115 mmHg in diastolic BP (DBP), 226 mg/dL in triglyceride and 33 mg/dL in HDL cholesterol at baseline was estimated to improve to the level without medications with a 1-year follow up. CONCLUSION: Lifestyle modification is useful for improving metabolic syndrome and its components. However, items of metabolic syndrome were improved, even when the abdominal circumference was greater than the normal value for Japanese men.
Nobuyuki Miyatake; Masafumi Fujii; Motohiko Miyachi; Izumi Tabata; Suzue Takeshi; Tomohiro Hirao; Takeyuki Numata
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-02-15
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  49     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2010  
Date Detail:
Created Date:  2010-02-15     Completed Date:  2010-05-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  261-5     Citation Subset:  IM    
Department of Hygiene, Faculty of Medicine, Kagawa University, Kagawa.
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MeSH Terms
Asian Continental Ancestry Group
Blood Glucose / metabolism
Blood Pressure
Cholesterol, HDL / blood
Follow-Up Studies
Life Style*
Metabolic Syndrome X / blood,  pathology,  physiopathology,  therapy*
Middle Aged
Obesity, Abdominal / pathology
Risk Factors
Triglycerides / blood
Reg. No./Substance:
0/Blood Glucose; 0/Cholesterol, HDL; 0/Triglycerides

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