Document Detail


Changes in liver blood flow after hepatectomy in conscious dogs.
MedLine Citation:
PMID:  8883239     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hepatic circulation after hepatectomy was investigated in conscious dogs under fasting and feeding conditions. After a 40% hepatectomy, both the hepatic arterial and portal blood flow were measured simultaneously using ultrasonic transit time flowmeters. During fasting, the total hepatic blood flow (i.e., the sum of arterial and portal blood flow) changed in a biphasic pattern after hepatectomy. The first peak (517.9 +/- 42.7 ml/min; 130.1% of preoperative flow) was seen on the 1st postoperative day (POD) and the second peak (444.8 +/- 25.6 ml/min; 112.7% of preoperative flow) occurred on the 7th POD. The portal flow demonstrated the same biphasic changes as the total hepatic flow, although the hepatic arterial flow showed only the first peak. A heart rate analysis suggested that the first peak was probably due to hyperdynamic circulatory conditions, as has been previously reported. In addition, the existence of the second peak was established by the present study. The postprandial hepatic blood flow decreased during the first 2 weeks postoperatively, but exceeded the presurgical levels on PODs 21 and 28.
Authors:
T Sato; A Yasui; S Kondo; M Kato; N Kameoka; Y Nimura
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Surgery today     Volume:  26     ISSN:  0941-1291     ISO Abbreviation:  Surg. Today     Publication Date:  1996  
Date Detail:
Created Date:  1997-01-24     Completed Date:  1997-01-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9204360     Medline TA:  Surg Today     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  688-93     Citation Subset:  IM    
Affiliation:
First Department of Surgery, Nagoya University School of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Dogs
Female
Food Deprivation
Hepatectomy*
Liver Circulation*
Male
Regional Blood Flow
Rheology
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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