| Changes in lipid composition of hepatocyte plasma membrane induced by overfeeding in duck. | |
| | |
MedLine Citation:
|
PMID: 15964231 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This experiment was carried out to examine the influence of overfeeding ducks with corn on the lipid composition of hepatocyte plasma membrane. Seventy-day-old male Mule ducks (Cairina moschata x Anas platyrhynchos) were overfed with corn for 12.5 days in order to induce fatty livers. The cholesterol and phospholipid contents were approximately 50% higher in hepatocyte plasma membranes from fatty livers compared to those of lean livers obtained from non-overfed ducks. However, the cholesterol/phospholipids molar ratio did not differ between both groups. Overfeeding induced a significant change in phospholipid composition of hepatocyte plasma membrane with a decrease in phosphatidylcholine proportion and conversely an increase in phosphatidylethanolamine. The fatty acid profile of phospholipids was also altered. In fatty hepatocyte plasma membrane, the overall proportion of polyunsaturated fatty acids (PUFA) was decreased and this was due to the decrease of some of, but not all, the PUFA. In addition, the proportions of oleic acid and n-9 series unsaturated fatty acids were higher in fatty than in lean liver membranes. This study provides evidence that overfeeding with a carbohydrate-rich corn-based diet induces a de novo hepatic lipogenesis in Mule duck which predominates over dietary lipid intake to change the lipid composition of the hepatocyte plasma membrane. |
| | |
Authors:
|
W Molee; M Bouillier-Oudot; A Auvergne; R Babilé |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology Volume: 141 ISSN: 1096-4959 ISO Abbreviation: Comp. Biochem. Physiol. B, Biochem. Mol. Biol. Publication Date: 2005 Aug |
Date Detail:
|
Created Date: 2005-07-19 Completed Date: 2005-10-18 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9516061 Medline TA: Comp Biochem Physiol B Biochem Mol Biol Country: England |
Other Details:
|
Languages: eng Pagination: 437-44 Citation Subset: IM |
Affiliation:
|
Ecole Nationale Supérieure Agronomique de Toulouse (ENSAT), Laboratoire de Zootechnie et Qualité des Produits Animaux, Avenue de l'Agrobiopole, BP 32607, F 31326 Castanet-Tolosan Cedex, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Body Weight Cell Membrane / chemistry, metabolism Dietary Carbohydrates / pharmacology Ducks / metabolism* Energy Intake* Fatty Acids / administration & dosage Fatty Liver / chemically induced, metabolism* Hepatocytes / chemistry, drug effects, metabolism* Male Membrane Lipids / analysis*, metabolism Organ Size Phospholipids / analysis, metabolism Species Specificity |
| Chemical | |
Reg. No./Substance:
|
0/Dietary Carbohydrates; 0/Fatty Acids; 0/Membrane Lipids; 0/Phospholipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The development of the pulmonary surfactant system in California sea lions.
Next Document: Evolutionarily conserved and divergent regulatory sequences in the fish rod opsin promoter.