Document Detail

Changes in intra-ocular pressure in the elderly during anaesthesia with propofol.
MedLine Citation:
PMID:  3259099     Owner:  NLM     Status:  MEDLINE    
Variations in intra-ocular pressure during anaesthesia were studied in two groups of 15 elderly patients selected randomly. The groups were not significantly different with regard to age, sex, weight or ASA classification. The first group received intravenous propofol as a bolus followed by a continuous infusion. The second group received a bolus of thiopentone followed by maintenance with enflurane. Intra-ocular pressure, heart rate and arterial pressure were measured before and after induction, after intubation and at the end of the operation. Overall, compared with baseline values, the results showed a decrease in intra-ocular pressure of 31% in group 1 and 17% in group 2, and a decrease in systolic arterial pressure of 14% in both groups.
Y Guedes; J C Rakotoseheno; M Leveque; F Mimouni; J P Egreteau
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Anaesthesia     Volume:  43 Suppl     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-06-01     Completed Date:  1988-06-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  58-60     Citation Subset:  AIM; IM    
Department of Anaesthesia, CHRU Morvan, Brest, France.
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MeSH Terms
Anesthesia, General
Anesthesia, Intravenous*
Anesthetics / pharmacology*
Enflurane / pharmacology
Hemodynamics / drug effects
Intraocular Pressure / drug effects*
Ophthalmologic Surgical Procedures
Phenols / pharmacology*
Thiopental / pharmacology
Reg. No./Substance:
0/Anesthetics; 0/Phenols; 13838-16-9/Enflurane; 2078-54-8/Propofol; 76-75-5/Thiopental

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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