Document Detail

Changes in internal carotid blood flow after CEA evaluated by transit-time flowmeter.
MedLine Citation:
PMID:  16242979     Owner:  NLM     Status:  MEDLINE    
AIM: The aim of this study was to investigate whether there was an association between the degree of the stenosis of the internal carotid artery (ICA) and post-operative increase of blood flow. METHODS AND MATERIALS: In 200 out of 660 patients undergoing carotid endarteriectomy (CEA) for a high-degree ICA stenosis, pre-operatively a bilateral selective carotid and intracerebral angiography was performed. The degree of the ipsilateral and contralateral stenosis was digitally assessed by using computer software according to the CC-Index. Intraoperatively, the pressure ratio over the stenosis (ICA/CCA) was measured by direct arterial puncture. Blood flow in the ICA was measured before and after CEA with an ultrasound flowmeter using the transit-time principle. These findings were correlated to the degree of stenosis revealed by angiographic analysis and the pressure ratio. RESULTS: Before CEA the median blood flow in the ICA was 171 ml/min (range 620 ml/min) with a significant (p<0.001) post-operative increase to 250 ml/min (range 875 ml/min). The median relative increase of flow (post-flow-pre-flow/pre-flow) was 42%. The pre-CEA flow volumes were dependent on the degree of stenosis and also the pressure ratio. The increase of flow following CEA correlated better with pressure ratio (r=-0.435, p<0.001), than the stenosis severity (r=0.319, p<0.001). Analysis of variance identified only the pressure gradient as an independent determinant of flow changes following CEA. CONCLUSIONS: The blood flow increase following CEA is mainly determined by the pressure gradient across the stenosis.
M Aleksic; V Matoussevitch; J Heckenkamp; J Brunkwall
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2005-10-20
Journal Detail:
Title:  European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery     Volume:  31     ISSN:  1078-5884     ISO Abbreviation:  Eur J Vasc Endovasc Surg     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2005-12-12     Completed Date:  2006-01-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9512728     Medline TA:  Eur J Vasc Endovasc Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  14-7     Citation Subset:  IM    
Division of Vascular Surgery, Department of Visceral- and Vascular Surgery, University of Cologne, Cologne, Germany.
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MeSH Terms
Aged, 80 and over
Blood Flow Velocity / physiology*
Carotid Artery, Internal / physiopathology*,  radiography,  ultrasonography
Carotid Stenosis / diagnosis,  physiopathology,  surgery*
Endarterectomy, Carotid*
Follow-Up Studies
Middle Aged
Postoperative Period
Retrospective Studies
Rheology / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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