Document Detail

Changes in the innervation and catecholamine concentrations in the myometrium of pregnant and non-pregnant sheep.
MedLine Citation:
PMID:  3953247     Owner:  NLM     Status:  MEDLINE    
The innervation of the myometrium in virgin, pregnant and post-partum ewes was examined using the SPG histofluorescence method and a high-performance liquid chromatographic catecholamine assay. In non-pregnant ewes, fluorescent axons were visible in all regions of the uterus. At 50 days of pregnancy the innervation was unchanged, but at 100 days axons were scarce over the whole uterus with the exception of the tubal extremities of the uterine horns. Noradrenaline concentrations were also significantly lower in late pregnancy, and significant variations occurred in different regions of the uterus, with the greatest concentrations present in the tubal extremities. At 13-16 weeks post partum, the density of innervation was variable, although the noradrenaline concentration was only slightly less than in virgin animals. Dopamine was also present in substantial quantities, but the mean concentrations remained unchanged during pregnancy.
J N Sigger; R Harding; R J Summers
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta anatomica     Volume:  125     ISSN:  0001-5180     ISO Abbreviation:  Acta Anat (Basel)     Publication Date:  1986  
Date Detail:
Created Date:  1986-04-14     Completed Date:  1986-04-14     Revised Date:  2007-07-02    
Medline Journal Info:
Nlm Unique ID:  0370272     Medline TA:  Acta Anat (Basel)     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  101-7     Citation Subset:  IM    
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MeSH Terms
Axons / ultrastructure
Dopamine / analysis*
Fallopian Tubes / cytology,  innervation
Microscopy, Fluorescence
Myometrium / cytology*,  innervation
Norepinephrine / analysis*
Pregnancy, Animal*
Uterus / cytology,  innervation
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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