| Changes in the initial slope of the QRS in ischemic patients and normal subjects undergoing scintigraphy with dipyridamole. | |
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MedLine Citation:
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PMID: 20950799 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The effect of dipyridamole (Dp) on the linear portion of the first major deflection of the QRS in human electrocardiograms (which we refer to as Fslope) was investigated in the context of myocardial perfusion imaging (MPI), in normal subjects (NS, n=19) and in patients with cardiovascular ischemia (as manifested by a positive MPI scan, n=53). In the majority of participants, Fslope decreased (84% of 19 NS and 77% of 53 patients, p=0.69). The decrease in Fslope was more pronounced in patients with ST-T deviation as compared to those without (32.6±24.5 vs. 22.4±23.1, p=0.24), and in patients vs. NS (24.9±23.5 vs. 19.6±23.4, p=0.44). A change in Fslope is a sensitive (but not specific) measure for detecting the effect of Dp on the myocardium in the setting of scintigraphy. |
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Authors:
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Guy Dori; Michal Gershinsky; Simona Ben-Haim; Basil S Lewis; Haim Bitterman |
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Publication Detail:
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Type: Journal Article Date: 2010-10-15 |
Journal Detail:
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Title: Computers in biology and medicine Volume: 40 ISSN: 1879-0534 ISO Abbreviation: Comput. Biol. Med. Publication Date: 2010 Nov-Dec |
Date Detail:
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Created Date: 2010-11-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1250250 Medline TA: Comput Biol Med Country: United States |
Other Details:
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Languages: eng Pagination: 869-75 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Internal Medicine, The Lady Davis Carmel Medical Center, 7, Michal Street, Haifa 34362, Israel. guydo@clalit.org.il |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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