| Changes in home versus clinic blood pressure with antihypertensive treatments: a meta-analysis. | |
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MedLine Citation:
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PMID: 18809791 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Home blood pressure (HBP) monitoring is recommended for assessing the effects of antihypertensive treatment, but it is not clear how the treatment-induced changes in HBP compare with the changes in clinic blood pressure (CBP). We searched PubMed using the terms "home or self-measured blood pressure," and selected articles in which the changes in CBP and HBP (using the upper arm oscillometric method) induced by antihypertensive drugs were presented. We performed a systematic review of 30 articles published before March 2008 that included a total of 6794 subjects. As there was significant heterogeneity in most of the outcomes, a random effects model was used for the meta-analyses. The mean changes (+/-SE) in CBP and HBP (systolic/diastolic) were -15.2+/-0.03/-10.3+/-0.03 mm Hg and -12.2+/-0.04/-8.0+/-0.04 mm Hg respectively, although there were wide varieties of differences in the reduction between HBP and CBP. The reductions in CBP were correlated with those of HBP (systolic BP; r=0.66, B=0.48, diastolic BP; r=0.71, B=0.52, P<0.001). In 7 studies that also included 24-hour BP monitoring, the reduction of HBP was greater than that of 24-hour BP in systolic (HBP; -12.6+/-0.06 mm Hg, 24-hour BP; -11.9+/-0.04 mm Hg, P<0.001). In 5 studies that included daytime and nighttime systolic BP separately, HBP decreased 15% more than daytime ambulatory BP and 30% more than nighttime ambulatory BP. In conclusion, HBP falls approximately 20% less than CBP with antihypertensive treatments. Daytime systolic BP falls 15% less and nighttime systolic BP falls 30% less than home systolic BP. |
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Authors:
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Joji Ishikawa; Deirdre J Carroll; Sujith Kuruvilla; Joseph E Schwartz; Thomas G Pickering |
Publication Detail:
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Type: Comparative Study; Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2008-09-22 |
Journal Detail:
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Title: Hypertension Volume: 52 ISSN: 1524-4563 ISO Abbreviation: Hypertension Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-10-23 Completed Date: 2008-11-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7906255 Medline TA: Hypertension Country: United States |
Other Details:
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Languages: eng Pagination: 856-64 Citation Subset: IM |
Affiliation:
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Department of Medicine, Center for Behavioral Cardiovascular Health, Columbia University Medical Center, New York 10032, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ambulatory Care Facilities* Antihypertensive Agents / therapeutic use* Blood Pressure / physiology* Blood Pressure Monitoring, Ambulatory* Circadian Rhythm / physiology Female Humans Hypertension / drug therapy*, physiopathology* Male Reproducibility of Results Treatment Outcome |
| Grant Support | |
ID/Acronym/Agency:
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P01-HL 47540/HL/NHLBI NIH HHS; R24HL76857/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents |
| Comments/Corrections | |
Comment In:
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Hypertension. 2008 Nov;52(5):795-6
[PMID:
18809788
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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