Document Detail

Changes in the hippocampus and the cerebellum resulting from hypoxic insults: frequency and distribution.
MedLine Citation:
PMID:  2782053     Owner:  NLM     Status:  MEDLINE    
Detailed neurohistological studies were undertaken on 35 cases of cardiac arrest, 17 of hypoglycaemia and 16 of status epilepticus. It was found that the frequency and pattern of selective vulnerability in the hippocampus were similar following cardiac arrest, hypoglycaemia and status epilepticus with the exception that the lateral limb of the dentate fascia was more frequently involved in hypoglycaemia than in the other two groups of cases. Within each group, however, CA1 was the most vulnerable. The cerebellum was less frequently affected in hypoglycaemia and status epilepticus than after cardiac arrest. These findings are compared with recent experimental studies in the rodent which have suggested that the pattern of neuronal damage in each of the three conditions is different.
T Ng; D I Graham; J H Adams; I Ford
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neuropathologica     Volume:  78     ISSN:  0001-6322     ISO Abbreviation:  Acta Neuropathol.     Publication Date:  1989  
Date Detail:
Created Date:  1989-10-19     Completed Date:  1989-10-19     Revised Date:  2007-11-09    
Medline Journal Info:
Nlm Unique ID:  0412041     Medline TA:  Acta Neuropathol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  438-43     Citation Subset:  IM    
Department of Neuropathology, University of Glasgow, Scotland.
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MeSH Terms
Cerebellum / pathology*,  physiopathology
Epilepsy / complications
Heart Arrest / complications
Hippocampus / pathology*,  physiopathology
Hypoglycemia / complications
Hypoxia, Brain / etiology,  pathology*

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