Document Detail

Changes in hepatic flow induced by continuous positive pressure ventilation in critically ill patients.
MedLine Citation:
PMID:  6754257     Owner:  NLM     Status:  MEDLINE    
To quantify the influence of continuous positive pressure ventilation (CPPV) on hepatic plasma flow (HPF) in 8 critically ill patients submitted to controlled ventilation, we measured simultaneously HPF by the indocyanine green dye (IGD) clearance and cardiac output (CO) by the thermodilution technique, while increasing PEEP from 0--20 cm H2O. CPPV induced a significant decrease in HPF which was related to the level of PEEP. A linear correlation was documented between HPF and CO; HPF remained a constant fraction of CO during CPPV. These results suggest that the decrease in CO is the most likely mechanism of the fall in HPF during CPPV.
F Bonnet; C Richard; P Glaser; M Lafay; R Guesde
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Critical care medicine     Volume:  10     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1982 Nov 
Date Detail:
Created Date:  1983-01-07     Completed Date:  1983-01-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  703-5     Citation Subset:  AIM; IM    
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MeSH Terms
Acute Disease
Indocyanine Green / diagnostic use,  metabolism
Liver / blood supply*
Middle Aged
Positive-Pressure Respiration*
Respiratory Insufficiency / therapy*
Reg. No./Substance:
3599-32-4/Indocyanine Green

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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