Document Detail

Changes in hemodynamics and respiration in rats with different resistance to acute hypoxia.
MedLine Citation:
PMID:  15514712     Owner:  NLM     Status:  MEDLINE    
Effects of acute hypoxia on hemodynamics and respiration were studied in acute experiments on narcotized rats. The animals were divided into groups characterized by high, low-, and medium- resistance to hypoxia by the time of respiration arrest during inhalation of gas mixture containing 3% O2. Hemodynamic parameters of highly resistant animals were higher than in low-resistant rats throughout the entire hypoxic period. The development of a rare (with prolonged inspiratory phase) respiratory rhythm in highly resistant rats is an adaptive reaction, which allows them longer tolerate hypoxia compared to low-resistant animals.
N V Sanotskaya; D D Matsievskii; M A Lebedeva
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  138     ISSN:  0007-4888     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-10-29     Completed Date:  2005-05-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  18-22     Citation Subset:  IM    
Laboratory of Respiration Pathophysiology, Bioengineering Laboratory, Institute of Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow.
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MeSH Terms
Adaptation, Physiological*
Anoxia / blood*,  physiopathology*
Rats, Inbred Strains

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